The Prospect of Identifying Resistance Mechanisms for Castrate-Resistant Prostate Cancer Using Circulating Tumor Cells: Is Epithelial-to-Mesenchymal Transition a Key Player?

Prostate cancer (PCa) is initially driven by excessive androgen receptor (AR) signaling with androgen deprivation therapy (ADT) being a major therapeutic approach to its treatment. However, the development of drug resistance is a significant limitation on the effectiveness of both first-line and mor...

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Detalles Bibliográficos
Autores principales: Khan, Tanzila, Scott, Kieran F., Becker, Therese M., Lock, John, Nimir, Mohammed, Ma, Yafeng, de Souza, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149487/
https://www.ncbi.nlm.nih.gov/pubmed/32292603
http://dx.doi.org/10.1155/2020/7938280

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