Virus Factories and Mini-Organelles Generated for Virus Replication

Many viruses replicate and assemble in subcellular microenvironments called virus factories or ‘viroplasm.’ Virus factories increase the efficiency of replication and at the same time protect viruses from antiviral defenses. We describe how viruses reorganize cellular membrane compartments and cytos...

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Detalles Bibliográficos
Autores principales: Wileman, T., Netherton, C.L., Powell, P.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149604/
http://dx.doi.org/10.1016/B978-0-12-394447-4.20102-8
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author Wileman, T.
Netherton, C.L.
Powell, P.P.
author_facet Wileman, T.
Netherton, C.L.
Powell, P.P.
author_sort Wileman, T.
collection PubMed
description Many viruses replicate and assemble in subcellular microenvironments called virus factories or ‘viroplasm.’ Virus factories increase the efficiency of replication and at the same time protect viruses from antiviral defenses. We describe how viruses reorganize cellular membrane compartments and cytoskeleton to generate these ‘mini-organelles’ and how these rearrangements parallel cellular responses to stress such as protein aggregation and DNA damage.
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spelling pubmed-71496042020-04-13 Virus Factories and Mini-Organelles Generated for Virus Replication Wileman, T. Netherton, C.L. Powell, P.P. Encyclopedia of Cell Biology Article Many viruses replicate and assemble in subcellular microenvironments called virus factories or ‘viroplasm.’ Virus factories increase the efficiency of replication and at the same time protect viruses from antiviral defenses. We describe how viruses reorganize cellular membrane compartments and cytoskeleton to generate these ‘mini-organelles’ and how these rearrangements parallel cellular responses to stress such as protein aggregation and DNA damage. 2016 2015-08-20 /pmc/articles/PMC7149604/ http://dx.doi.org/10.1016/B978-0-12-394447-4.20102-8 Text en Copyright © 2016 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Wileman, T.
Netherton, C.L.
Powell, P.P.
Virus Factories and Mini-Organelles Generated for Virus Replication
title Virus Factories and Mini-Organelles Generated for Virus Replication
title_full Virus Factories and Mini-Organelles Generated for Virus Replication
title_fullStr Virus Factories and Mini-Organelles Generated for Virus Replication
title_full_unstemmed Virus Factories and Mini-Organelles Generated for Virus Replication
title_short Virus Factories and Mini-Organelles Generated for Virus Replication
title_sort virus factories and mini-organelles generated for virus replication
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149604/
http://dx.doi.org/10.1016/B978-0-12-394447-4.20102-8
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