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An update on treatment options for primary sclerosing cholangitis
Primary sclerosing cholangitis is a chronic cholestatic liver disease defined by strictures of the biliary tree which could ultimately lead to liver cirrhosis and cholangiocarcinoma. Although the exact underlying etiology of this disorder is not fully understood, the pathology is believed to be caus...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shaheed Beheshti University of Medical Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149806/ https://www.ncbi.nlm.nih.gov/pubmed/32308932 |
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author | Iravani, Shahrokh Dooghaie-Moghadam, Arash Razavi-Khorasani, Niloofar Moazzami, Bobak Dowlati Beirami, Amirreza Mansour-Ghanaei, Alireza Majidzadeh-A, Keivan Mehrvar, Azim Khoshdel, Alireza Nasiri Toosi, Mohssen Sadeghi, Amir |
author_facet | Iravani, Shahrokh Dooghaie-Moghadam, Arash Razavi-Khorasani, Niloofar Moazzami, Bobak Dowlati Beirami, Amirreza Mansour-Ghanaei, Alireza Majidzadeh-A, Keivan Mehrvar, Azim Khoshdel, Alireza Nasiri Toosi, Mohssen Sadeghi, Amir |
author_sort | Iravani, Shahrokh |
collection | PubMed |
description | Primary sclerosing cholangitis is a chronic cholestatic liver disease defined by strictures of the biliary tree which could ultimately lead to liver cirrhosis and cholangiocarcinoma. Although the exact underlying etiology of this disorder is not fully understood, the pathology is believed to be caused by immune mediated mechanisms. Growing body of evidence suggests several treatment modalities mainly focusing on the inflammation aspect of this disorder. However, there is still no consensus regarding the best treatment option for these patients. Thus, the present study aimed to review the current treatment options for patients with primary sclerosing cholangitis. |
format | Online Article Text |
id | pubmed-7149806 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Shaheed Beheshti University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-71498062020-04-17 An update on treatment options for primary sclerosing cholangitis Iravani, Shahrokh Dooghaie-Moghadam, Arash Razavi-Khorasani, Niloofar Moazzami, Bobak Dowlati Beirami, Amirreza Mansour-Ghanaei, Alireza Majidzadeh-A, Keivan Mehrvar, Azim Khoshdel, Alireza Nasiri Toosi, Mohssen Sadeghi, Amir Gastroenterol Hepatol Bed Bench Review Article Primary sclerosing cholangitis is a chronic cholestatic liver disease defined by strictures of the biliary tree which could ultimately lead to liver cirrhosis and cholangiocarcinoma. Although the exact underlying etiology of this disorder is not fully understood, the pathology is believed to be caused by immune mediated mechanisms. Growing body of evidence suggests several treatment modalities mainly focusing on the inflammation aspect of this disorder. However, there is still no consensus regarding the best treatment option for these patients. Thus, the present study aimed to review the current treatment options for patients with primary sclerosing cholangitis. Shaheed Beheshti University of Medical Sciences 2020 /pmc/articles/PMC7149806/ /pubmed/32308932 Text en ©2020 RIGLD, Research Institute for Gastroenterology and Liver Diseases This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Iravani, Shahrokh Dooghaie-Moghadam, Arash Razavi-Khorasani, Niloofar Moazzami, Bobak Dowlati Beirami, Amirreza Mansour-Ghanaei, Alireza Majidzadeh-A, Keivan Mehrvar, Azim Khoshdel, Alireza Nasiri Toosi, Mohssen Sadeghi, Amir An update on treatment options for primary sclerosing cholangitis |
title | An update on treatment options for primary sclerosing cholangitis |
title_full | An update on treatment options for primary sclerosing cholangitis |
title_fullStr | An update on treatment options for primary sclerosing cholangitis |
title_full_unstemmed | An update on treatment options for primary sclerosing cholangitis |
title_short | An update on treatment options for primary sclerosing cholangitis |
title_sort | update on treatment options for primary sclerosing cholangitis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149806/ https://www.ncbi.nlm.nih.gov/pubmed/32308932 |
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