Cargando…

Mycoplasma gallisepticum triggers immune damage in the chicken thymus by activating the TLR-2/MyD88/NF-κB signaling pathway and NLRP3 inflammasome

Previous studies reported that Mycoplasma gallisepticum (MG) causes immune dysregulation in chickens. However, the underlying mechanisms of immune dysregulation in chickens are still unclear. The thymus is a primary lymphoid organ where the proliferation, differentiation and selection of T-lymphocyt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Chunli, Li, Jichang, Zhang, Wei, Shah, Syed Waqas Ali, Ishfaq, Muhammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149927/ https://www.ncbi.nlm.nih.gov/pubmed/32276652 http://dx.doi.org/10.1186/s13567-020-00777-x

Ejemplares similares

Gut Microbiota Dysbiosis Aggravates Mycoplasma gallisepticum Colonization in the Chicken Lung
por: Wang, Jian, et al.
Publicado: (2021)

Baicalin Attenuates Mycoplasma gallisepticum-Induced Inflammation via Inhibition of the TLR2-NF-κB Pathway in Chicken and DF-1 Cells
por: Wu, Zhiyong, et al.
Publicado: (2019)

Baicalin mitigated Mycoplasma gallisepticum-induced structural damage and attenuated oxidative stress and apoptosis in chicken thymus through the Nrf2/HO-1 defence pathway
por: Li, Jichang, et al.
Publicado: (2019)

gga-miR-146c Activates TLR6/MyD88/NF-κB Pathway through Targeting MMP16 to Prevent Mycoplasma Gallisepticum (HS Strain) Infection in Chickens
por: Zhang, Kang, et al.
Publicado: (2019)

Antagonistic Effects Of Baicalin On Mycoplasma gallisepticum-Induced Inflammation And Apoptosis By Restoring Energy Metabolism In The Chicken Lungs
por: Ishfaq, Muhammad, et al.
Publicado: (2019)

Atorvastatin suppresses NLRP3 inflammasome activation in intracerebral hemorrhage via TLR4- and MyD88-dependent pathways
por: Chen, Duo, et al.
Publicado: (2022)

MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs
por: Ge, Shuang, et al.
Publicado: (2021)

Mycoplasma gallisepticum Infection Impaired the Structural Integrity and Immune Function of Bursa of Fabricius in Chicken: Implication of Oxidative Stress and Apoptosis
por: Zhang, Wei, et al.
Publicado: (2020)

Pharmacokinetic/pharmacodynamic profiles of baicalin against Mycoplasma gallisepticum in an in vivo infection model
por: Bao, Jiaxin, et al.
Publicado: (2021)

Baicalein ameliorates TNBS-induced colitis by suppressing TLR4/MyD88 signaling cascade and NLRP3 inflammasome activation in mice
por: Luo, Xiaoping, et al.
Publicado: (2017)

Current status of vaccine research, development, and challenges of vaccines for Mycoplasma gallisepticum
por: Ishfaq, Muhammad, et al.
Publicado: (2020)

Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
por: Chen, Junbin, et al.
Publicado: (2020)

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer
por: Block, Matthew S., et al.
Publicado: (2018)

Inflammatory Role of TLR-MyD88 Signaling in Multiple Sclerosis
por: Zheng, Chao, et al.
Publicado: (2020)

MyD88 in macrophages protects against colitis via inhibiting the activation of NLRP3 inflammasome in epithelial cells
por: Liu, Shi, et al.
Publicado: (2022)

Detection of Mycoplasma gallisepticum in broiler chickens by PCR
por: Mahmmoud, Ebtehal N., et al.
Publicado: (2022)

LuQi Formula Ameliorates Myocardial Fibrosis by Suppressing TLR4/MyD88/NF-κB Pathway and NLRP3 Inflammasome Activation in Mice with Myocardial Infarction
por: Zhang, Xiaoqing, et al.
Publicado: (2022)

From monogenic lupus to TLR7/MyD88-targeted therapy
por: Wang, Min, et al.
Publicado: (2022)

Isolation and Molecular Characterization of Mycoplasma gallisepticum and Mycoplasma synoviae in Chickens in Sudan
por: Khalifa, Khalda A., et al.
Publicado: (2013)

TLR2/MyD88/NF-κB Pathway, Reactive Oxygen Species, Potassium Efflux Activates NLRP3/ASC Inflammasome during Respiratory Syncytial Virus Infection
por: Segovia, Jesus, et al.
Publicado: (2012)

Curcumin Represses NLRP3 Inflammasome Activation via TLR4/MyD88/NF-κB and P2X7R Signaling in PMA-Induced Macrophages
por: Kong, Fanqi, et al.
Publicado: (2016)

MUC1 attenuates neutrophilic airway inflammation in asthma by reducing NLRP3 inflammasome-mediated pyroptosis through the inhibition of the TLR4/MyD88/NF-κB pathway
por: Liu, Lu, et al.
Publicado: (2023)

Forsythia suspensa (Thunb.) Vahl extract ameliorates ulcerative colitis via inhibiting NLRP3 inflammasome activation through the TLR4/MyD88/NF‐κB pathway
por: Tong, Xiao, et al.
Publicado: (2023)

Polypharmacology-based approach for screening TCM against coinfection of Mycoplasma gallisepticum and Escherichia coli
por: Bao, Jiaxin, et al.
Publicado: (2022)

Arachidonic acid metabolism is elevated in Mycoplasma gallisepticum and Escherichia coli co-infection and induces LTC4 in serum as the biomarker for detecting poultry respiratory disease
por: Wu, Zhiyong, et al.
Publicado: (2020)

Baicalin inhibits inflammation caused by coinfection of Mycoplasma gallisepticum and Escherichia coli involving IL-17 signaling pathway
por: Wu, Zhiyong, et al.
Publicado: (2020)

Tanshinone IIA reduces pyroptosis in rats with coronary microembolization by inhibiting the TLR4/MyD88/NF-κB/NLRP3 pathway
por: Li, Hao-Liang, et al.
Publicado: (2022)

Resveratrol pretreatment alleviates NLRP3 inflammasome-mediated cardiomyocyte pyroptosis by targeting TLR4/MyD88/NF-κB signaling cascade in coronary microembolization-induced myocardial damage
por: Luo, Chang-Jun, et al.
Publicado: (2023)

Methylsulfonylmethane ameliorates inflammation via NF-κB and ERK/JNK-MAPK signaling pathway in chicken trachea and HD11 cells during Mycoplasma gallisepticum infection
por: Miao, Yusong, et al.
Publicado: (2022)

Baicalin ameliorates oxidative stress and apoptosis by restoring mitochondrial dynamics in the spleen of chickens via the opposite modulation of NF-κB and Nrf2/HO-1 signaling pathway during Mycoplasma gallisepticum infection
por: Ishfaq, Muhammad, et al.
Publicado: (2019)

MyD88 and beyond: a perspective on MyD88-targeted therapeutic approach for modulation of host immunity
por: Saikh, Kamal U.
Publicado: (2021)

Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88‐Dependent Inflammation
por: Luo, Wu, et al.
Publicado: (2022)

Absorption of N-acetylcysteine in Healthy and Mycoplasma gallisepticum-Infected Chickens
por: Petkova, Tsvetelina, et al.
Publicado: (2021)

A MyD88 meddles with survival
por: Bashyam, Hema
Publicado: (2007)

Role of MyD88 in Adenovirus Keratitis
por: Zhou, Xiaohong, et al.
Publicado: (2016)

Porcine Reproductive and Respiratory Syndrome Virus Induces IL-1β Production Depending on TLR4/MyD88 Pathway and NLRP3 Inflammasome in Primary Porcine Alveolar Macrophages
por: Bi, Jing, et al.
Publicado: (2014)

Panax quinquefolius L. Saponins Protect Myocardial Ischemia Reperfusion No-Reflow Through Inhibiting the Activation of NLRP3 Inflammasome via TLR4/MyD88/NF-κB Signaling Pathway
por: Yu, Ping, et al.
Publicado: (2021)

Expression and significance of the TLR4/MyD88 signaling pathway in ovarian epithelial cancers
por: Kim, Ki Hyung, et al.
Publicado: (2012)

TLR4/MyD88 signaling determines the metastatic potential of breast cancer cells
por: Wu, Kunlin, et al.
Publicado: (2018)

TLR/MyD88-mediated Innate Immunity in Intestinal Graft-versus-Host Disease
por: Lee, Young-Kwan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ji1enlr15gkoevldlvt0k20pbj