Alpha-Helical Peptide Assemblies: Giving New Function to Designed Structures

The design of alpha-helical tectons for self-assembly is maturing as a science. We have now reached the point where many different coiled-coil topologies can be reliably produced and validated in synthetic systems and the field is now moving on towards more complex, discrete structures and applicati...

Descripción completa

Detalles Bibliográficos
Autores principales: Bromley, Elizabeth H.C., Channon, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150058/
https://www.ncbi.nlm.nih.gov/pubmed/21999998
http://dx.doi.org/10.1016/B978-0-12-415906-8.00001-7
_version_ 1783520945531518976
author Bromley, Elizabeth H.C.
Channon, Kevin J.
author_facet Bromley, Elizabeth H.C.
Channon, Kevin J.
author_sort Bromley, Elizabeth H.C.
collection PubMed
description The design of alpha-helical tectons for self-assembly is maturing as a science. We have now reached the point where many different coiled-coil topologies can be reliably produced and validated in synthetic systems and the field is now moving on towards more complex, discrete structures and applications. Similarly the design of infinite or fiber assemblies has also matured, with the creation fibers that have been modified or functionalized in a variety of ways. This chapter discusses the progress made in both of these areas as well as outlining the challenges still to come.
format Online
Article
Text
id pubmed-7150058
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Elsevier Inc.
record_format MEDLINE/PubMed
spelling pubmed-71500582020-04-13 Alpha-Helical Peptide Assemblies: Giving New Function to Designed Structures Bromley, Elizabeth H.C. Channon, Kevin J. Prog Mol Biol Transl Sci Article The design of alpha-helical tectons for self-assembly is maturing as a science. We have now reached the point where many different coiled-coil topologies can be reliably produced and validated in synthetic systems and the field is now moving on towards more complex, discrete structures and applications. Similarly the design of infinite or fiber assemblies has also matured, with the creation fibers that have been modified or functionalized in a variety of ways. This chapter discusses the progress made in both of these areas as well as outlining the challenges still to come. Elsevier Inc. 2011 2011-10-14 /pmc/articles/PMC7150058/ /pubmed/21999998 http://dx.doi.org/10.1016/B978-0-12-415906-8.00001-7 Text en Copyright © 2011 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Bromley, Elizabeth H.C.
Channon, Kevin J.
Alpha-Helical Peptide Assemblies: Giving New Function to Designed Structures
title Alpha-Helical Peptide Assemblies: Giving New Function to Designed Structures
title_full Alpha-Helical Peptide Assemblies: Giving New Function to Designed Structures
title_fullStr Alpha-Helical Peptide Assemblies: Giving New Function to Designed Structures
title_full_unstemmed Alpha-Helical Peptide Assemblies: Giving New Function to Designed Structures
title_short Alpha-Helical Peptide Assemblies: Giving New Function to Designed Structures
title_sort alpha-helical peptide assemblies: giving new function to designed structures
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150058/
https://www.ncbi.nlm.nih.gov/pubmed/21999998
http://dx.doi.org/10.1016/B978-0-12-415906-8.00001-7
work_keys_str_mv AT bromleyelizabethhc alphahelicalpeptideassembliesgivingnewfunctiontodesignedstructures
AT channonkevinj alphahelicalpeptideassembliesgivingnewfunctiontodesignedstructures

Ejemplares similares