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Genetic Basis of Salmonella Enteritidis Pathogenesis in Chickens

Salmonella Enteritidis (SE) is the predominant cause of the food-borne salmonellosis in humans, in part because this serotype has the unique ability to contaminate chicken eggs without causing discernible illness in the infected birds. Attempts to develop effective vaccines and eradicate SE from chi...

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Autores principales: Shah, Devendra H., Elder, Jacob R., Chiok, Kim L., Paul, Narayan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150355/
http://dx.doi.org/10.1016/B978-0-12-802582-6.00010-0
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author Shah, Devendra H.
Elder, Jacob R.
Chiok, Kim L.
Paul, Narayan C.
author_facet Shah, Devendra H.
Elder, Jacob R.
Chiok, Kim L.
Paul, Narayan C.
author_sort Shah, Devendra H.
collection PubMed
description Salmonella Enteritidis (SE) is the predominant cause of the food-borne salmonellosis in humans, in part because this serotype has the unique ability to contaminate chicken eggs without causing discernible illness in the infected birds. Attempts to develop effective vaccines and eradicate SE from chickens are undermined by significant limitations in our current understanding of the genetic basis of pathogenesis of SE in this reservoir host. In this chapter, we summarize the infection kinetics and provide an overview of the current understanding of genetic factors underlying SE infection in the chicken host. We also discuss the important knowledge gaps that, if addressed, will improve our understanding of the complex biology of SE in young chickens and in egg laying hens.
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spelling pubmed-71503552020-04-13 Genetic Basis of Salmonella Enteritidis Pathogenesis in Chickens Shah, Devendra H. Elder, Jacob R. Chiok, Kim L. Paul, Narayan C. Producing Safe Eggs Article Salmonella Enteritidis (SE) is the predominant cause of the food-borne salmonellosis in humans, in part because this serotype has the unique ability to contaminate chicken eggs without causing discernible illness in the infected birds. Attempts to develop effective vaccines and eradicate SE from chickens are undermined by significant limitations in our current understanding of the genetic basis of pathogenesis of SE in this reservoir host. In this chapter, we summarize the infection kinetics and provide an overview of the current understanding of genetic factors underlying SE infection in the chicken host. We also discuss the important knowledge gaps that, if addressed, will improve our understanding of the complex biology of SE in young chickens and in egg laying hens. 2017 2016-09-16 /pmc/articles/PMC7150355/ http://dx.doi.org/10.1016/B978-0-12-802582-6.00010-0 Text en Copyright © 2017 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Shah, Devendra H.
Elder, Jacob R.
Chiok, Kim L.
Paul, Narayan C.
Genetic Basis of Salmonella Enteritidis Pathogenesis in Chickens
title Genetic Basis of Salmonella Enteritidis Pathogenesis in Chickens
title_full Genetic Basis of Salmonella Enteritidis Pathogenesis in Chickens
title_fullStr Genetic Basis of Salmonella Enteritidis Pathogenesis in Chickens
title_full_unstemmed Genetic Basis of Salmonella Enteritidis Pathogenesis in Chickens
title_short Genetic Basis of Salmonella Enteritidis Pathogenesis in Chickens
title_sort genetic basis of salmonella enteritidis pathogenesis in chickens
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150355/
http://dx.doi.org/10.1016/B978-0-12-802582-6.00010-0
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