Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vectors: Implications in Gene Therapy and Genome Editing

We have reported that of the 10 most commonly used adeno-associated virus (AAV) serotype vectors, AAV6 is the most efficient in transducing primary human hematopoietic stem cells (HSCs) in vitro, as well as in vivo. More recently, polyvinyl alcohol (PVA), was reported to be a superior replacement fo...

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Detalles Bibliográficos
Autores principales: Yang, Hua, Qing, Keyun, Keeler, Geoffrey D., Yin, Ling, Mietzsch, Mario, Ling, Chen, Hoffman, Brad E., Agbandje-McKenna, Mavis, Tan, Mengqun, Wang, Wei, Srivastava, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150427/
https://www.ncbi.nlm.nih.gov/pubmed/32276210
http://dx.doi.org/10.1016/j.omtn.2020.03.009

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