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RAS/RAF mutations in tumor samples and cell-free DNA from plasma and bone marrow aspirates in multiple myeloma patients

Purpose: To evaluate the detection of gene mutations in bone marrow biopsy and circulating free DNA (cfDNA) from plasma in multiple myeloma (MM). Experimental design: We used cell-free DNA from plasma and bone marrow to test BRAF V600, KRAS G12/G13, NRAS G12/G13 and NRAS Q61 mutations using multiple...

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Detalles Bibliográficos
Autores principales: Li, Qian, Huang, Helen J, Ma, Jing, Wang, Yafei, Cao, Zeng, Karlin-Neumann, George, Janku, Filip, Liu, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150446/
https://www.ncbi.nlm.nih.gov/pubmed/32284750
http://dx.doi.org/10.7150/jca.43729