MiR-186 bidirectionally regulates cisplatin sensitivity of ovarian cancer cells via suppressing targets PIK3R3 and PTEN and upregulating APAF1 expression

Ovarian cancer is a highly lethal malignancy in the female reproductive system. Platinum drugs, represented by cisplatin, are the first-line chemotherapeutic agents for treatment of various malignancies including ovarian cancer, but drug resistance leads to chemotherapy failure. MicroRNAs emerged as...

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Detalles Bibliográficos
Autores principales: Xiang, Ying, Chen, Ya-Jun, Yan, Yun-Bo, Liu, Yu, Qiu, Jiao, Tan, Rui-Qiao, Tian, Qing, Guan, Li, Niu, Shuai-Shuai, Xin, Hong-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150455/
https://www.ncbi.nlm.nih.gov/pubmed/32284740
http://dx.doi.org/10.7150/jca.41135

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