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PACAP neuropeptide promotes Hepatocellular Protection via CREB-KLF4 dependent autophagy in mouse liver Ischemia Reperfusion Injury

Organ ischemia reperfusion injury (IRI), associated with acute hepatocyte death, remains an unresolved problem in clinical orthotopic liver transplantation (OLT). Autophagy, an intracellular self-digesting progress, is responsible for cell reprograming required to regain post-stress homeostasis. Met...

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Detalles Bibliográficos
Autores principales: Xue, Zhengze, Zhang, Yu, Liu, Yuanxing, Zhang, Cheng, Shen, Xiu-da, Gao, Feng, Busuttil, Ronald W., Zheng, Shusen, Kupiec-Weglinski, Jerzy W., Ji, Haofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150481/
https://www.ncbi.nlm.nih.gov/pubmed/32292507
http://dx.doi.org/10.7150/thno.42354