Effective control of tumor growth through spatial and temporal control of theranostic sodium iodide symporter (NIS) gene expression using a heat-inducible gene promoter in engineered mesenchymal stem cells

Purpose: The tumor homing characteristics of mesenchymal stem cells (MSCs) make them attractive vehicles for the tumor-specific delivery of therapeutic agents, such as the sodium iodide symporter (NIS). NIS is a theranostic protein that allows non-invasive monitoring of the in vivo biodistribution o...

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Detalles Bibliográficos
Autores principales: Tutter, Mariella, Schug, Christina, Schmohl, Kathrin A., Urnauer, Sarah, Schwenk, Nathalie, Petrini, Matteo, Lokerse, Wouter J. M., Zach, Christian, Ziegler, Sibylle, Bartenstein, Peter, Weber, Wolfgang A., Wagner, Ernst, Lindner, Lars H., Nelson, Peter J., Spitzweg, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150485/
https://www.ncbi.nlm.nih.gov/pubmed/32292510
http://dx.doi.org/10.7150/thno.41489

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