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G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome
Rationale: Epigenetic mechanisms are fundamental processes that can modulate gene expression, allowing cellular adaptation to environmental conditions. Hypoxia is an important factor known to initiate the metastatic cascade in cancer, activating cell motility and invasion by silencing cell adhesion...
Autores principales: | Casciello, Francesco, Al-Ejeh, Fares, Miranda, Mariska, Kelly, Greg, Baxter, Eva, Windloch, Karolina, Gannon, Frank, Lee, Jason S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150496/ https://www.ncbi.nlm.nih.gov/pubmed/32292512 http://dx.doi.org/10.7150/thno.41453 |
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