Mechanistic Insights into Protein Stability and Self-aggregation in GLUT1 Genetic Variants Causing GLUT1-Deficiency Syndrome

Human sodium-independent glucose cotransporter 1 (hGLUT1) has been studied for its tetramerization and multimerization at the cell surface. Homozygous or compound heterozygous mutations in hGLUT1 elicit GLUT1-deficiency syndrome (GLUT1-DS), a metabolic disorder, which results in impaired glucose tra...

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Detalles Bibliográficos
Autores principales: Raja, Mobeen, Kinne, Rolf K. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Topical Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150661/
https://www.ncbi.nlm.nih.gov/pubmed/32025761
http://dx.doi.org/10.1007/s00232-020-00108-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150661/
https://www.ncbi.nlm.nih.gov/pubmed/32025761
http://dx.doi.org/10.1007/s00232-020-00108-3

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