Cargando…

Resveratrol Prevents Cognitive Impairment in Type 2 Diabetic Mice by Upregulating Nrf2 Expression and Transcriptional Level

PURPOSE: This study aimed to determine whether the natural antioxidant resveratrol (RSV) prevents type 2 diabetes mellitus (T2DM)-induced cognitive impairment and to explore whether redox-associated factor nuclear factor erythroid 2-related factor 2 (Nrf2) plays a critical role in the neuroprotectiv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xiaoxiao, Fang, Hui, Xu, Gang, Yang, Ying, Xu, Ruizhe, Liu, Qiang, Xue, Xiangyu, Liu, Jiaqi, Wang, Hezhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150671/ https://www.ncbi.nlm.nih.gov/pubmed/32308456 http://dx.doi.org/10.2147/DMSO.S243560

Ejemplares similares

Resveratrol Prevents Cognitive Impairment in Type 2 Diabetic Mice by Upregulating Nrf2 Expression and Transcriptional Level [Corrigendum]
Publicado: (2020)

Resveratrol Prevents Diabetic Cardiomyopathy by Increasing Nrf2 Expression and Transcriptional Activity
por: Wang, Guan, et al.
Publicado: (2018)

Imine Resveratrol Analogues: Molecular Design, Nrf2 Activation and SAR Analysis
por: Li, Chang, et al.
Publicado: (2014)

Resveratrol Alleviates Endotoxin-Induced Myocardial Toxicity via the Nrf2 Transcription Factor
por: Hao, Enkui, et al.
Publicado: (2013)

Nuclear transcription factor Nrf2 suppresses prostate cancer cells growth and migration through upregulating ferroportin
por: Xue, Dong, et al.
Publicado: (2016)

Resveratrol prevents osteoporosis by upregulating FoxO1 transcriptional activity
por: Feng, Yan-Ling, et al.
Publicado: (2018)

Resveratrol Attenuates Heat Stress-Induced Impairment of Meat Quality in Broilers by Regulating the Nrf2 Signaling Pathway
por: Zhao, Yiyang, et al.
Publicado: (2022)

Nrf2 transcriptional upregulation of IDH2 to tune mitochondrial dynamics and rescue angiogenic function of diabetic EPCs
por: Dai, Xiaozhen, et al.
Publicado: (2022)

PSMD12 promotes glioma progression by upregulating the expression of Nrf2
por: Wang, Zhongyong, et al.
Publicado: (2021)

Vitamin D Improves Cognitive Impairment and Alleviates Ferroptosis via the Nrf2 Signaling Pathway in Aging Mice
por: Li, Jiaxin, et al.
Publicado: (2023)

Soluble Epoxide Hydrolase Inhibition Protected against Diabetic Cardiomyopathy through Inducing Autophagy and Reducing Apoptosis Relying on Nrf2 Upregulation and Transcription Activation
por: Fang, Qin, et al.
Publicado: (2022)

DNA Demethylation Upregulated Nrf2 Expression in Alzheimer’s Disease Cellular Model
por: Cao, Huimin, et al.
Publicado: (2016)

Anti-inflammatory effect of resveratrol attenuates the severity of diabetic neuropathy by activating the Nrf2 pathway
por: Zhang, Wanli, et al.
Publicado: (2021)

Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury
por: Kim, Eun Nim, et al.
Publicado: (2018)

Transcriptional Regulation by Nrf2
por: Tonelli, Claudia, et al.
Publicado: (2018)

ACE2 Expression Is Upregulated in Inflammatory Corneal Epithelial Cells and Attenuated by Resveratrol
por: Jiang, Zhixin, et al.
Publicado: (2021)

Strigolactone GR24 upregulates target genes of the cytoprotective transcription factor Nrf2 in skeletal muscle
por: Modi, Shalem Raju, et al.
Publicado: (2018)

Emodin attenuates diabetic kidney disease by inhibiting ferroptosis via upregulating Nrf2 expression
por: Ji, Jing, et al.
Publicado: (2023)

MEF2A transcriptionally upregulates the expression of ZEB2 and CTNNB1 in colorectal cancer to promote tumor progression
por: Xiao, Qing, et al.
Publicado: (2021)

Defining the Functional Targets of Cap‘n’collar Transcription Factors NRF1, NRF2, and NRF3
por: Ibrahim, Lara, et al.
Publicado: (2020)

Nrf2 Inhibits the Progression of Parkinson’s Disease by Upregulating AABR07032261.5 to Repress Pyroptosis
por: Zhong, Yunxiao, et al.
Publicado: (2022)

Prevention of Diabetic Nephropathy by Sulforaphane: Possible Role of Nrf2 Upregulation and Activation
por: Cui, Wenpeng, et al.
Publicado: (2012)

Curcumin reverses erastin-induced chondrocyte ferroptosis by upregulating Nrf2
por: Zhou, Yizhao, et al.
Publicado: (2023)

Resveratrol mediates its anti-cancer effects by Nrf2 signaling pathway activation
por: Alavi, Matin, et al.
Publicado: (2021)

Sulforaphane Attenuation of Type 2 Diabetes-Induced Aortic Damage Was Associated with the Upregulation of Nrf2 Expression and Function
por: Wang, Yonggang, et al.
Publicado: (2014)

Co-Treatment With Resveratrol and FGF1 Protects Against Acute Liver Toxicity After Doxorubicin Treatment via the AMPK/NRF2 Pathway
por: Xu, Xianchou, et al.
Publicado: (2022)

Resveratrol pretreatment attenuates injury and promotes proliferation of neural stem cells following oxygen-glucose deprivation/reoxygenation by upregulating the expression of Nrf2, HO-1 and NQO1 in vitro
por: Shen, Changbo, et al.
Publicado: (2016)

Sargassum fusiforme Fucoidan SP2 Extends the Lifespan of Drosophila melanogaster by Upregulating the Nrf2-Mediated Antioxidant Signaling Pathway
por: Zhang, Ya, et al.
Publicado: (2019)

Resveratrol mitigates the oxidative stress mediated by hypoxic-ischemic brain injury in neonatal rats via Nrf2/HO-1 pathway
por: Gao, Yan, et al.
Publicado: (2018)

Resveratrol reduces the apoptosis induced by cigarette smoke extract by upregulating MFN2
por: Song, Chao, et al.
Publicado: (2017)

Upregulation of nuclear factor E2-related factor 2 (Nrf2) represses the replication of herpes simplex virus type 1
por: Zhang, Li, et al.
Publicado: (2022)

Resveratrol and FGF1 Synergistically Ameliorates Doxorubicin-Induced Cardiotoxicity via Activation of SIRT1-NRF2 Pathway
por: Lu, Guangping, et al.
Publicado: (2022)

Roles of CNC Transcription Factors NRF1 and NRF2 in Cancer
por: Sekine, Hiroki, et al.
Publicado: (2021)

miR-200a Attenuated Doxorubicin-Induced Cardiotoxicity through Upregulation of Nrf2 in Mice
por: Hu, Xiaoping, et al.
Publicado: (2019)

Synergistic inhibition of mesothelioma cell growth by the combination of clofarabine and resveratrol involves Nrf2 downregulation
por: Lee, Yoon-Jin, et al.
Publicado: (2012)

Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway
por: Feng, Zhuo, et al.
Publicado: (2021)

Activation of AMPK/p38/Nrf2 is involved in resveratrol alleviating myocardial ischemia-reperfusion injury in diabetic rats as an endogenous antioxidant stress feedback
por: Xu, Guiping, et al.
Publicado: (2022)

Probucol Prevents Diabetes-Induced Retinal Neuronal Degeneration through Upregulating Nrf2
por: Liu, Heng-Wei, et al.
Publicado: (2020)

SAT-455 Mouse Thyroid Responds to Iodine Overload by Transcriptionally Enhancing the Keap1/Nrf2 Antioxidant Response and by Upregulating Nrf2-Dependent and Independent Inflammatory and Fibrosis Pathways
por: Chartoumpekis, Dionysios V, et al.
Publicado: (2020)

Upregulation of MicroRNA-34a Sensitizes Ovarian Cancer Cells to Resveratrol by Targeting Bcl-2
por: Yao, Shangli, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qm8mgra2456sljgc5tt95e488l