Cargando…

Elevated Serum Level of Cytokeratin 18 M65ED Is an Independent Indicator of Cardiometabolic Disorders

BACKGROUND: Recent studies have suggested that cell death might be involved in the pathophysiology of metabolic disorders. The cytokeratin 18 (CK18) fragment, as a cell death marker, plays an important role in nonalcoholic fatty liver disease (NAFLD). However, only a limited number of studies have f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qian, Lingling, Zhang, Lei, Wu, Liang, Zhang, Jing, Fang, Qichen, Hou, Xuhong, Gao, Qiongmei, Li, Huating, Jia, Weiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150704/ https://www.ncbi.nlm.nih.gov/pubmed/32337295 http://dx.doi.org/10.1155/2020/5198359

Ejemplares similares

Complementary Role of Fibroblast Growth Factor 21 and Cytokeratin 18 in Monitoring the Different Stages of Nonalcoholic Fatty Liver Disease
por: Wu, Guangyu, et al.
Publicado: (2017)

FGF21/adiponectin ratio predicts deterioration in glycemia: a 4.6-year prospective study in China
por: Liu, Dan, et al.
Publicado: (2021)

Fibroblast Growth Factor 21 is Related to Atherosclerosis Independent of Nonalcoholic Fatty Liver Disease and Predicts Atherosclerotic Cardiovascular Events
por: Wu, Liang, et al.
Publicado: (2020)

Bifidobacterium adolescentis Alleviates Liver Steatosis and Steatohepatitis by Increasing Fibroblast Growth Factor 21 Sensitivity
por: Long, Xiaoxue, et al.
Publicado: (2021)

Decreased Abundance of Akkermansia muciniphila Leads to the Impairment of Insulin Secretion and Glucose Homeostasis in Lean Type 2 Diabetes
por: Zhang, Jing, et al.
Publicado: (2021)

Clinical Values of Elevated Serum Cytokeratin-18 Levels in Hepatitis: A Meta-Analysis
por: Yang, Zhao Hui, et al.
Publicado: (2015)

Serum Fibroblast Growth Factor 19 Levels Are Decreased in Chinese Subjects With Impaired Fasting Glucose and Inversely Associated With Fasting Plasma Glucose Levels
por: Fang, Qichen, et al.
Publicado: (2013)

Serum Cytokeratin-18 Levels for Liver Fibrosis Prediction
por: Caviglia, Gian Paolo, et al.
Publicado: (2015)

Serum Level of Cytokeratin 18 (M65) as a Prognostic Marker of High Cardiovascular Disease Risk in Individuals with Non-Alcoholic Fatty Liver Disease
por: Pagano, Sabrina, et al.
Publicado: (2023)

Accuracy of cytokeratin 18 (M30 and M65) in detecting non-alcoholic steatohepatitis and fibrosis: A systematic review and meta-analysis
por: Lee, Jenny, et al.
Publicado: (2020)

Serum and urine periostin and cytokeratin-18 in children with congenital obstructive nephropathy
por: Turczyn, Agnieszka, et al.
Publicado: (2022)

Cytokeratin 8/18 expression indicates a poor prognosis in squamous cell carcinomas of the oral cavity
por: Fillies, Thomas, et al.
Publicado: (2006)

The Significance of Caspase-Cleaved Cytokeratin 18 in Pleural Effusion
por: Lee, Keu Sung, et al.
Publicado: (2014)

Cytokeratin-18 in Diagnosis of HCC in Patients with Liver Cirrhosis
por: Ismail, Saber A, et al.
Publicado: (2017)

An analysis of Cyclin D1, Cytokeratin 5/6 and Cytokeratin 8/18 expression in breast papillomas and papillary carcinomas
por: Wang, Yu, et al.
Publicado: (2013)

Chemotherapy increases caspase-cleaved cytokeratin 18 in the serum of breast cancer patients
por: Ulukaya, Engin, et al.
Publicado: (2011)

Serum Cytokeratin 18 as a Metastatic and Therapeutic Marker for Extramammary Paget’s Disease
por: URANO-TAKAOKA, Mariko, et al.
Publicado: (2022)

Cytokeratin 8/18 overexpression and complex formation as an indicator of GST-P positive foci transformation into hepatocellular carcinomas
por: Kakehashi, Anna, et al.
Publicado: (2009)

Cytokeratin 5/6 and cytokeratin 8/18 expression in triple negative breast cancers: clinicopathologic significance in South-Asian population
por: Hashmi, Atif Ali, et al.
Publicado: (2018)

Cytokeratin 18 Is Not Required for Morphogenesis of Developing Prostates but Contributes to Adult Prostate Regeneration
por: Zhang, Chenlu, et al.
Publicado: (2013)

The SIAMS-ED Trial: A National, Independent, Multicentre Study on Cardiometabolic and Hormonal Impairment of Men with Erectile Dysfunction Treated with Vardenafil
por: Isidori, Andrea M., et al.
Publicado: (2014)

PKC epsilon-related kinase associates with and phosphorylates cytokeratin 8 and 18
Publicado: (1992)

Considerations for the use of plasma cytokeratin 18 as a biomarker in pancreatic cancer
por: Dive, C, et al.
Publicado: (2010)

The application of cytokeratin-18 as a biomarker for drug-induced liver injury
por: Korver, Samantha, et al.
Publicado: (2021)

Plasma Cytokeratin-18 Fragment Level Reflects the Metabolic Phenotype in Obesity
por: Goralska, Joanna, et al.
Publicado: (2023)

Visceral Obesity and Cytokeratin-18 Antigens as Early Biomarkers of Liver Damage
por: de Alteriis, Giulia, et al.
Publicado: (2023)

Effects of Exercise Intervention on Type 2 Diabetes Patients With Abdominal Obesity and Low Thigh Circumference (EXTEND): Study Protocol for a Randomized Controlled Trial
por: Liu, Dan, et al.
Publicado: (2022)

Cytokeratin 8/18 protects breast cancer cell lines from TRAIL-induced apoptosis
por: Bozza, William P., et al.
Publicado: (2018)

High Serum Caspase-Cleaved Cytokeratin-18 Levels and Mortality of Traumatic Brain Injury Patients
por: Lorente, Leonardo, et al.
Publicado: (2019)

Cytokeratin19-2g2, a Novel Fragment of Cytokeratin19 in Serum, Indicating a More Invasive Behavior and Worse Prognosis in Breast Cancer Patients
por: Kong, Yanan, et al.
Publicado: (2013)

Total and caspase-cleaved cytokeratin 18 in chronic cholecystitis: A prospective study
por: Simopoulos, Constantinos, et al.
Publicado: (2008)

Cytokeratin 18 in plasma of patients with gastrointestinal adenocarcinoma as a biomarker of tumour response
por: Scott, L C, et al.
Publicado: (2009)

Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis
por: Cha, Seung-Ick, et al.
Publicado: (2012)

Cytokeratin 18, Alanine Aminotransferase, Platelets and Triglycerides Predict the Presence of Nonalcoholic Steatohepatitis
por: Cao, Wei, et al.
Publicado: (2013)

Association of liver biomarkers and cytokeratin-18 in Nonalcoholic fatty liver disease patients
por: Altaf, Benash, et al.
Publicado: (2020)

Challenges in enumeration of CTCs in breast cancer using techniques independent of cytokeratin expression
por: Castle, John, et al.
Publicado: (2017)

Elevated Squamous Cell Carcinoma Antigen, Cytokeratin 19 Fragment, and Carcinoembryonic Antigen Levels in Diabetic Nephropathy
por: Chen, Jianzhong, et al.
Publicado: (2017)

Serum Cytokeratin-18 Is Associated with NOX2-Generated Oxidative Stress in Patients with Nonalcoholic Fatty Liver
por: Del Ben, M., et al.
Publicado: (2014)

Serum Levels of Caspase-Cleaved Cytokeratin-18 and Mortality Are Associated in Severe Septic Patients: Pilot Study
por: Lorente, Leonardo, et al.
Publicado: (2014)

Significance of Serum Cytokeratin-18 in Prediction of Hepatocellular Carcinoma in Chronic Hepatitis C Infected Egyptian Patients
por: El-Zefzafy, Wafaa, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ebpe3g95kbq0pq5agfmhm87ugo