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A Rational Design of a Biphasic Dissolution Setup—Modelling of Biorelevant Kinetics for a Ritonavir Hot-Melt Extruded Amorphous Solid Dispersion

Biphasic dissolution systems achieved good predictability for the in vivo performance of several formulations of poorly water-soluble drugs by characterizing dissolution, precipitation, re-dissolution, and absorption. To achieve a high degree of predictive performance, acceptor media, aqueous phase...

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Detalles Bibliográficos
Autores principales:	Denninger, Alexander, Westedt, Ulrich, Rosenberg, Jörg, Wagner, Karl G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150762/ https://www.ncbi.nlm.nih.gov/pubmed/32155962 http://dx.doi.org/10.3390/pharmaceutics12030237

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