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Molecular Basis of the Ternary Interaction between NS1 of the 1918 Influenza A Virus, PI3K, and CRK

The 1918 influenza A virus (IAV) caused the worst flu pandemic in human history. Non-structural protein 1 (NS1) is an important virulence factor of the 1918 IAV and antagonizes host antiviral immune responses. NS1 increases virulence by activating phosphoinositide 3-kinase (PI3K) via binding to the...

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Detalles Bibliográficos
Autores principales:	Dubrow, Alyssa, Lin, Sirong, Savage, Nowlan, Shen, Qingliang, Cho, Jae-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150778/ https://www.ncbi.nlm.nih.gov/pubmed/32244879 http://dx.doi.org/10.3390/v12030338

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