Cargando…

The Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) gH/gL Complex Is the Predominant Neutralizing Antigenic Determinant in KSHV-Infected Individuals

Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi’s sarcoma (KS), one of the most prevalent cancers of people living with HIV/AIDS in sub-Saharan Africa. The seroprevalence for KSHV is high in the region, and no prophylactic vaccine against the virus is available. In...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mortazavi, Yasaman, Lidenge, Salum J., Tran, Tara, West, John T., Wood, Charles, Tso, For Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150787/ https://www.ncbi.nlm.nih.gov/pubmed/32111001 http://dx.doi.org/10.3390/v12030256

Ejemplares similares

Antibodies Targeting KSHV gH/gL Reveal Distinct Neutralization Mechanisms
por: Fricke, Thomas, et al.
Publicado: (2022)

BALB/c mice immunized with a combination of virus-like particles incorporating Kaposi sarcoma-associated herpesvirus (KSHV) envelope glycoproteins gpK8.1, gB, and gH/gL induced comparable serum neutralizing antibody activity to UV-inactivated KSHV
por: Barasa, Anne K, et al.
Publicado: (2017)

Review of the distribution of Kaposi's sarcoma-associated herpesvirus (KSHV) in Africa in relation to the incidence of Kaposi's sarcoma
por: Dedicoat, M, et al.
Publicado: (2003)

Efficient lytic induction of kaposi's sarcoma-associated herpesvirus (KSHV) by the anthracyclines
por: Kang, Hyunju, et al.
Publicado: (2014)

Transient induction of lytic Kaposi's sarcoma-associated herpesvirus (KSHV) genes in KSHV-infected endothelial cells exposed to hypoxia
por: Velasco, P, et al.
Publicado: (2009)

Parasite infection is associated with Kaposi's sarcoma associated herpesvirus (KSHV) in Ugandan women
por: Wakeham, Katie, et al.
Publicado: (2011)

Next-Generation Sequencing in the Understanding of Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Biology
por: Strahan, Roxanne, et al.
Publicado: (2016)

Clinical Manifestations of Kaposi Sarcoma Herpesvirus Lytic Activation: Multicentric Castleman Disease (KSHV–MCD) and the KSHV Inflammatory Cytokine Syndrome
por: Polizzotto, Mark N., et al.
Publicado: (2012)

Corrigendum: Clinical manifestations of Kaposi sarcoma herpesvirus lytic activation: multicentric Castleman disease (KSHV–MCD) and the KSHV inflammatory cytokine syndrome
por: Polizzotto, Mark N., et al.
Publicado: (2017)

Post-Translational Modifications of Kaposi’s Sarcoma-Associated Herpesvirus Regulatory Proteins – SUMO and KSHV
por: Campbell, Mel, et al.
Publicado: (2012)

Lytic Reactivation of the Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Is Accompanied by Major Nucleolar Alterations
por: Atari, Nofar, et al.
Publicado: (2022)

Lack of CD8(+) T-cell co-localization with Kaposi’s sarcoma-associated herpesvirus infected cells in Kaposi’s sarcoma tumors
por: Lidenge, Salum J., et al.
Publicado: (2020)

KSHV regulation of fibulins in Kaposi’s sarcoma: implications for tumorigenesis
por: Alcendor, Donald, et al.
Publicado: (2010)

Disrupting Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Latent Replication with a Small Molecule Inhibitor
por: Berwanger, Aylin, et al.
Publicado: (2023)

Kaposi sarcoma herpesvirus (KSHV)-associated lymphomas are associated with markedly elevated serum IL-10, elevated IL-6, IL-17 and circulating KSHV
por: Uldrick, Thomas S, et al.
Publicado: (2012)

Infection with Kaposi's sarcoma-associated herpesvirus (KSHV) and human immunodeficiency virus (HIV) in relation to the risk and clinical presentation of Kaposi's sarcoma in Uganda
por: Newton, R, et al.
Publicado: (2003)

The interferon-stimulated gene product oligoadenylate synthetase-like protein enhances replication of Kaposi’s sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF20 protein
por: Bussey, Kendra A., et al.
Publicado: (2018)

NDRG1 facilitates lytic replication of Kaposi’s sarcoma-associated herpesvirus by maintaining the stability of the KSHV helicase
por: Dong, Lianghui, et al.
Publicado: (2021)

KSHV/HHV-8 and HIV infection in Kaposi's sarcoma development
por: Pyakurel, Pawan, et al.
Publicado: (2007)

Viral and Immunological Analytes are Poor Predictors of the Clinical Treatment Response in Kaposi’s Sarcoma Patients
por: Lidenge, Salum J., et al.
Publicado: (2020)

A conserved Eph family receptor-binding motif on the gH/gL complex of Kaposi’s sarcoma-associated herpesvirus and rhesus monkey rhadinovirus
por: Großkopf, Anna K., et al.
Publicado: (2018)

The Murid Herpesvirus-4 gH/gL Binds to Glycosaminoglycans
por: Gillet, Laurent, et al.
Publicado: (2008)

Experimental Transmission of Kaposi's Sarcoma–Associated Herpesvirus (Kshv/Hhv-8) to Scid-Hu Thy/Liv Mice
por: Dittmer, D., et al.
Publicado: (1999)

Kaposi’s sarcoma-associated herpesvirus (KSHV) serum DNA not associated with subsequent non-Hodgkin’s lymphoma (NHL) risk
por: Beachler, Dan, et al.
Publicado: (2010)

3D culture conditions support Kaposi’s sarcoma herpesvirus (KSHV) maintenance and viral spread in endothelial cells
por: Dubich, Tatyana, et al.
Publicado: (2021)

Proteomic Profiling Identifies Kaposi’s Sarcoma-Associated Herpesvirus (KSHV)-Encoded LANA(SIM)-Associated Proteins in Hypoxia
por: Liu, Xiaoqing, et al.
Publicado: (2021)

Antibody epitope profiling of the KSHV LANA protein using VirScan
por: Bennett, Sydney J., et al.
Publicado: (2022)

Upregulation of Cell Surface Glycoproteins in Correlation with KSHV LANA in the Kaposi Sarcoma Tumor Microenvironment
por: Privatt, Sara R., et al.
Publicado: (2023)

NEDDylation Is Essential for Kaposi’s Sarcoma-Associated Herpesvirus Latency and Lytic Reactivation and Represents a Novel Anti-KSHV Target
por: Hughes, David J., et al.
Publicado: (2015)

KSHV-mediated ROS induction defines novel therapeutic targets in Kaposi’s sarcoma
por: Cavallin, Lucas E, et al.
Publicado: (2010)

Molecular and Cellular Mechanisms of KSHV Oncogenesis of Kaposi's Sarcoma Associated with HIV/AIDS
por: Cavallin, Lucas E., et al.
Publicado: (2014)

PAN’s Labyrinth: Molecular Biology of Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) PAN RNA, a Multifunctional Long Noncoding RNA
por: Rossetto, Cyprian C., et al.
Publicado: (2014)

Kaposi’s sarcoma-associated herpesvirus (KSHV) utilizes the NDP52/CALCOCO2 selective autophagy receptor to disassemble processing bodies
por: Robinson, Carolyn-Ann, et al.
Publicado: (2023)

KSHV 3.0: A State-of-the-Art Annotation of the Kaposi’s Sarcoma-Associated Herpesvirus Transcriptome Using Cross-Platform Sequencing
por: Prazsák, István, et al.
Publicado: (2023)

Crystal structure of the conserved herpesvirus fusion regulator complex gH–gL
por: Chowdary, Tirumala K., et al.
Publicado: (2010)

Relationship between salivary shedding and seropositivity for Kaposi’s sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) among South African children and adults: insights on why EBV infection is ubiquitous and KSHV is not
por: Butler, Lisa, et al.
Publicado: (2010)

Kaposi's Sarcoma Associated-Herpes Virus (KSHV) Seroprevalence in Pregnant Women in South Africa
por: Malope-Kgokong, Babatyi I, et al.
Publicado: (2010)

Suppression of galectin-3 in KSHV infected DMVEC cells and Kaposi's sarcoma: implications for tumorigenesis
por: Alcendor, DJ, et al.
Publicado: (2009)

Inhibition of Tip60 Reduces Lytic and Latent Gene Expression of Kaposi’s Sarcoma-Associated Herpes Virus (KSHV) and Proliferation of KSHV-Infected Tumor Cells
por: Simpson, Sydney, et al.
Publicado: (2018)

Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Induces the Oncogenic miR-17-92 Cluster and Down-Regulates TGF-β Signaling
por: Choi, Hong Seok, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_dij5sko7b7b4t2fr0ilt35n039