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A Novel Bivalent Mannosylated Targeting Ligand Displayed on Nanoparticles Selectively Targets Anti-Inflammatory M2 Macrophages
Persistent activation of macrophages (MP)s into a proinflammatory M1 or anti-inflammatory M2 phenotype plays a role in several pathological conditions, including autoimmune diseases, fibrosis, infections, atherosclerosis and tumor development. The mannose receptor (MR, CD206), expressed at low level...
Autores principales: | Chen, Peiming, Zhang, Xiaoping, Venosa, Alessandro, Lee, In Heon, Myers, Daniel, Holloway, Jennifer A., Prud’homme, Robert K., Gao, Dayuan, Szekely, Zoltan, Laskin, Jeffery D., Laskin, Debra L., Sinko, Patrick J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150811/ https://www.ncbi.nlm.nih.gov/pubmed/32182675 http://dx.doi.org/10.3390/pharmaceutics12030243 |
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