Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe

Three autochthonous cases of Zika virus occurred in southern France in August 2019. Diagnosis relied on serology and transcription-mediated amplification. Attempts for virus isolation and ZIKV genome RT-PCR detection remained negative. Since the index case was not identified, we addressed the issue...

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Autores principales: Durand, Guillaume A., Piorkowski, Géraldine, Thirion, Laurence, Ninove, Laetitia, Giron, Sandra, Zandotti, Christine, Denis, Jessica, Badaut, Cyril, Failloux, Anna-Bella, Grard, Gilda, Leparc-Goffart, Isabelle, de Lamballerie, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150815/
https://www.ncbi.nlm.nih.gov/pubmed/32182748
http://dx.doi.org/10.3390/v12030296
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author Durand, Guillaume A.
Piorkowski, Géraldine
Thirion, Laurence
Ninove, Laetitia
Giron, Sandra
Zandotti, Christine
Denis, Jessica
Badaut, Cyril
Failloux, Anna-Bella
Grard, Gilda
Leparc-Goffart, Isabelle
de Lamballerie, Xavier
author_facet Durand, Guillaume A.
Piorkowski, Géraldine
Thirion, Laurence
Ninove, Laetitia
Giron, Sandra
Zandotti, Christine
Denis, Jessica
Badaut, Cyril
Failloux, Anna-Bella
Grard, Gilda
Leparc-Goffart, Isabelle
de Lamballerie, Xavier
author_sort Durand, Guillaume A.
collection PubMed
description Three autochthonous cases of Zika virus occurred in southern France in August 2019. Diagnosis relied on serology and transcription-mediated amplification. Attempts for virus isolation and ZIKV genome RT-PCR detection remained negative. Since the index case was not identified, we addressed the issue of genotyping and geographical origin by performing hemi-nested PCR and sequencing in the Pr gene. Analysis of 16 genotype-specific Single Nucleotides Polymorphisms identified the Asian genotype and suggested a Southeast Asia origin.
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spelling pubmed-71508152020-04-20 Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe Durand, Guillaume A. Piorkowski, Géraldine Thirion, Laurence Ninove, Laetitia Giron, Sandra Zandotti, Christine Denis, Jessica Badaut, Cyril Failloux, Anna-Bella Grard, Gilda Leparc-Goffart, Isabelle de Lamballerie, Xavier Viruses Brief Report Three autochthonous cases of Zika virus occurred in southern France in August 2019. Diagnosis relied on serology and transcription-mediated amplification. Attempts for virus isolation and ZIKV genome RT-PCR detection remained negative. Since the index case was not identified, we addressed the issue of genotyping and geographical origin by performing hemi-nested PCR and sequencing in the Pr gene. Analysis of 16 genotype-specific Single Nucleotides Polymorphisms identified the Asian genotype and suggested a Southeast Asia origin. MDPI 2020-03-09 /pmc/articles/PMC7150815/ /pubmed/32182748 http://dx.doi.org/10.3390/v12030296 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Durand, Guillaume A.
Piorkowski, Géraldine
Thirion, Laurence
Ninove, Laetitia
Giron, Sandra
Zandotti, Christine
Denis, Jessica
Badaut, Cyril
Failloux, Anna-Bella
Grard, Gilda
Leparc-Goffart, Isabelle
de Lamballerie, Xavier
Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe
title Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe
title_full Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe
title_fullStr Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe
title_full_unstemmed Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe
title_short Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe
title_sort vector-borne transmission of the zika virus asian genotype in europe
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150815/
https://www.ncbi.nlm.nih.gov/pubmed/32182748
http://dx.doi.org/10.3390/v12030296
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