The Determination of HIV-1 RT Mutation Rate, Its Possible Allosteric Effects, and Its Implications on Drug Resistance

The high mutation rate of the human immunodeficiency virus type 1 (HIV-1) plays a major role in treatment resistance, from the development of vaccines to therapeutic drugs. In addressing the crux of the issue, various attempts to estimate the mutation rate of HIV-1 resulted in a large range of 10(−5...

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Detalles Bibliográficos
Autores principales: Yeo, Joshua Yi, Goh, Ghin-Ray, Su, Chinh Tran-To, Gan, Samuel Ken-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150816/
https://www.ncbi.nlm.nih.gov/pubmed/32182845
http://dx.doi.org/10.3390/v12030297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150816/
https://www.ncbi.nlm.nih.gov/pubmed/32182845
http://dx.doi.org/10.3390/v12030297

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