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Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot

Autophagy is a highly conserved degradation mechanism that is essential for maintaining cellular homeostasis. In human disease, autophagy pathways are frequently deregulated and there is immense interest in targeting autophagy for therapeutic approaches. Accordingly, there is a need to determine aut...

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Detalles Bibliográficos
Autores principales: Humbert, Magali, Morán, María, de la Cruz-Ojeda, Patricia, Muntané, Jordi, Wiedmer, Tabea, Apostolova, Nadezda, McKenna, Sharon L., Velasco, Guillermo, Balduini, Walter, Eckhart, Leopold, Janji, Bassam, Sampaio-Marques, Belém, Ludovico, Paula, Žerovnik, Eva, Langer, Rupert, Perren, Aurel, Engedal, Nikolai, Tschan, Mario P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150830/
https://www.ncbi.nlm.nih.gov/pubmed/32245178
http://dx.doi.org/10.3390/biology9030059