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Formulation and In-Vitro Characterization of Chitosan-Nanoparticles Loaded with the Iron Chelator Deferoxamine Mesylate (DFO)

The objective of this study was to develop chitosan (CS) nanoparticles (NPs) loaded with deferoxamine mesylate (DFO) for slow release of this iron-chelating drug. Drug nanoencapsulation was performed via ionic gelation of chitosan using sodium tripolyphosphate (TPP) as cross-linker. Nanoparticles wi...

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Detalles Bibliográficos
Autores principales:	Lazaridou, Maria, Christodoulou, Evi, Nerantzaki, Maria, Kostoglou, Margaritis, Lambropoulou, Dimitra A., Katsarou, Angeliki, Pantopoulos, Kostas, Bikiaris, Dimitrios N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150847/ https://www.ncbi.nlm.nih.gov/pubmed/32156022 http://dx.doi.org/10.3390/pharmaceutics12030238

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