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SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation

Hepatitis B virus (HBV) replication is controlled by four promoters (preS1, preS2, Cp, and Xp) and two enhancers (EnhI and EnhII). EnhII stimulates Cp activity to regulate the transcriptions of precore, core, polymerase, and pregenomic RNAs, and therefore, EnhII/Cp is essential for the regulation of...

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Detalles Bibliográficos
Autores principales:	Yang, Hua, Mo, Jiayin, Xiang, Qi, Zhao, Peiyi, Song, Yunting, Yang, Ge, Wu, Kailang, Liu, Yingle, Liu, Weiyong, Wu, Jianguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150879/ https://www.ncbi.nlm.nih.gov/pubmed/32121397 http://dx.doi.org/10.3390/v12030273

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