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PERK-Mediated Unfolded Protein Response Signaling Restricts Replication of the Tick-Borne Flavivirus Langat Virus

The unfolded protein response (UPR) maintains protein-folding homeostasis in the endoplasmic reticulum (ER) and has been implicated as both beneficial and detrimental to flavivirus infection. Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK), a sensor of the UPR, is commonly associated...

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Detalles Bibliográficos
Autores principales:	Lewy, Tyler G., Offerdahl, Danielle K., Grabowski, Jeffrey M., Kellman, Eliza, Mlera, Luwanika, Chiramel, Abhilash, Bloom, Marshall E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150897/ https://www.ncbi.nlm.nih.gov/pubmed/32197325 http://dx.doi.org/10.3390/v12030328

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