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The Effect of Cooling on the Degree of Crystallinity, Solid-State Properties, and Dissolution Rate of Multi-Component Hot-Melt Extruded Solid Dispersions

The effect of cooling on the degree of crystallinity, solid-state and dissolution properties of multi-component hot-melt extruded solid dispersions [SD] is of great interest for the successful formulation of amorphous SDs and is an area that is unreported, especially in the context of improving the...

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Detalles Bibliográficos
Autores principales: Hurley, Dean, Davis, Mark, Walker, Gavin M., Lyons, John G., Higginbotham, Clement L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150909/
https://www.ncbi.nlm.nih.gov/pubmed/32121578
http://dx.doi.org/10.3390/pharmaceutics12030212