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Peste des Petits Ruminants at the Wildlife–Livestock Interface in the Northern Albertine Rift and Nile Basin, East Africa

In the recent past, peste des petits ruminants (PPR) emerged in East Africa causing outbreaks in small livestock across different countries, with evidences of spillover to wildlife. In order to understand better PPR at the wildlife–livestock interface, we investigated patterns of peste des petits ru...

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Autores principales: Fernandez Aguilar, Xavier, Mahapatra, Mana, Begovoeva, Mattia, Kalema-Zikusoka, Gladys, Driciru, Margaret, Ayebazibwe, Chrisostom, Adwok, David Solomon, Kock, Michael, Lukusa, Jean-Paul Kabemba, Muro, Jesus, Marco, Ignasi, Colom-Cadena, Andreu, Espunyes, Johan, Meunier, Natascha, Cabezón, Oscar, Caron, Alexandre, Bataille, Arnaud, Libeau, Genevieve, Parekh, Krupali, Parida, Satya, Kock, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150925/
https://www.ncbi.nlm.nih.gov/pubmed/32156067
http://dx.doi.org/10.3390/v12030293
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author Fernandez Aguilar, Xavier
Mahapatra, Mana
Begovoeva, Mattia
Kalema-Zikusoka, Gladys
Driciru, Margaret
Ayebazibwe, Chrisostom
Adwok, David Solomon
Kock, Michael
Lukusa, Jean-Paul Kabemba
Muro, Jesus
Marco, Ignasi
Colom-Cadena, Andreu
Espunyes, Johan
Meunier, Natascha
Cabezón, Oscar
Caron, Alexandre
Bataille, Arnaud
Libeau, Genevieve
Parekh, Krupali
Parida, Satya
Kock, Richard
author_facet Fernandez Aguilar, Xavier
Mahapatra, Mana
Begovoeva, Mattia
Kalema-Zikusoka, Gladys
Driciru, Margaret
Ayebazibwe, Chrisostom
Adwok, David Solomon
Kock, Michael
Lukusa, Jean-Paul Kabemba
Muro, Jesus
Marco, Ignasi
Colom-Cadena, Andreu
Espunyes, Johan
Meunier, Natascha
Cabezón, Oscar
Caron, Alexandre
Bataille, Arnaud
Libeau, Genevieve
Parekh, Krupali
Parida, Satya
Kock, Richard
author_sort Fernandez Aguilar, Xavier
collection PubMed
description In the recent past, peste des petits ruminants (PPR) emerged in East Africa causing outbreaks in small livestock across different countries, with evidences of spillover to wildlife. In order to understand better PPR at the wildlife–livestock interface, we investigated patterns of peste des petits ruminants virus (PPRV) exposure, disease outbreaks, and viral sequences in the northern Albertine Rift. PPRV antibodies indicated a widespread exposure in apparently healthy wildlife from South Sudan (2013) and Uganda (2015, 2017). African buffaloes and Uganda kobs <1-year-old from Queen Elizabeth National Park (2015) had antibodies against PPRV N-antigen and local serosurvey captured a subsequent spread of PPRV in livestock. Outbreaks with PPR-like syndrome in sheep and goats were recorded around the Greater Virunga Landscape in Kasese (2016), Kisoro and Kabale (2017) from western Uganda, and in North Kivu (2017) from eastern Democratic Republic of the Congo (DRC). This landscape would not be considered typical for PPR persistence as it is a mixed forest–savannah ecosystem with mostly sedentary livestock. PPRV sequences from DRC (2017) were identical to strains from Burundi (2018) and confirmed a transboundary spread of PPRV. Our results indicate an epidemiological linkage between epizootic cycles in livestock and exposure in wildlife, denoting the importance of PPR surveillance on wild artiodactyls for both conservation and eradication programs.
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spelling pubmed-71509252020-04-20 Peste des Petits Ruminants at the Wildlife–Livestock Interface in the Northern Albertine Rift and Nile Basin, East Africa Fernandez Aguilar, Xavier Mahapatra, Mana Begovoeva, Mattia Kalema-Zikusoka, Gladys Driciru, Margaret Ayebazibwe, Chrisostom Adwok, David Solomon Kock, Michael Lukusa, Jean-Paul Kabemba Muro, Jesus Marco, Ignasi Colom-Cadena, Andreu Espunyes, Johan Meunier, Natascha Cabezón, Oscar Caron, Alexandre Bataille, Arnaud Libeau, Genevieve Parekh, Krupali Parida, Satya Kock, Richard Viruses Article In the recent past, peste des petits ruminants (PPR) emerged in East Africa causing outbreaks in small livestock across different countries, with evidences of spillover to wildlife. In order to understand better PPR at the wildlife–livestock interface, we investigated patterns of peste des petits ruminants virus (PPRV) exposure, disease outbreaks, and viral sequences in the northern Albertine Rift. PPRV antibodies indicated a widespread exposure in apparently healthy wildlife from South Sudan (2013) and Uganda (2015, 2017). African buffaloes and Uganda kobs <1-year-old from Queen Elizabeth National Park (2015) had antibodies against PPRV N-antigen and local serosurvey captured a subsequent spread of PPRV in livestock. Outbreaks with PPR-like syndrome in sheep and goats were recorded around the Greater Virunga Landscape in Kasese (2016), Kisoro and Kabale (2017) from western Uganda, and in North Kivu (2017) from eastern Democratic Republic of the Congo (DRC). This landscape would not be considered typical for PPR persistence as it is a mixed forest–savannah ecosystem with mostly sedentary livestock. PPRV sequences from DRC (2017) were identical to strains from Burundi (2018) and confirmed a transboundary spread of PPRV. Our results indicate an epidemiological linkage between epizootic cycles in livestock and exposure in wildlife, denoting the importance of PPR surveillance on wild artiodactyls for both conservation and eradication programs. MDPI 2020-03-07 /pmc/articles/PMC7150925/ /pubmed/32156067 http://dx.doi.org/10.3390/v12030293 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fernandez Aguilar, Xavier
Mahapatra, Mana
Begovoeva, Mattia
Kalema-Zikusoka, Gladys
Driciru, Margaret
Ayebazibwe, Chrisostom
Adwok, David Solomon
Kock, Michael
Lukusa, Jean-Paul Kabemba
Muro, Jesus
Marco, Ignasi
Colom-Cadena, Andreu
Espunyes, Johan
Meunier, Natascha
Cabezón, Oscar
Caron, Alexandre
Bataille, Arnaud
Libeau, Genevieve
Parekh, Krupali
Parida, Satya
Kock, Richard
Peste des Petits Ruminants at the Wildlife–Livestock Interface in the Northern Albertine Rift and Nile Basin, East Africa
title Peste des Petits Ruminants at the Wildlife–Livestock Interface in the Northern Albertine Rift and Nile Basin, East Africa
title_full Peste des Petits Ruminants at the Wildlife–Livestock Interface in the Northern Albertine Rift and Nile Basin, East Africa
title_fullStr Peste des Petits Ruminants at the Wildlife–Livestock Interface in the Northern Albertine Rift and Nile Basin, East Africa
title_full_unstemmed Peste des Petits Ruminants at the Wildlife–Livestock Interface in the Northern Albertine Rift and Nile Basin, East Africa
title_short Peste des Petits Ruminants at the Wildlife–Livestock Interface in the Northern Albertine Rift and Nile Basin, East Africa
title_sort peste des petits ruminants at the wildlife–livestock interface in the northern albertine rift and nile basin, east africa
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150925/
https://www.ncbi.nlm.nih.gov/pubmed/32156067
http://dx.doi.org/10.3390/v12030293
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