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Genetic Analysis of Peroxisomal Genes Required for Longevity in a Yeast Model of Citrin Deficiency
Citrin is a liver-specific mitochondrial aspartate–glutamate carrier encoded by SLC25A13. Citrin deficiency caused by SLC25A13 mutation results in carbohydrate toxicity, citrullinemia type II, and fatty liver diseases, the mechanisms of some of which remain unknown. Citrin shows a functional homolog...
Autores principales: | Chalermwat, Chalongchai, Thosapornvichai, Thitipa, Jensen, Laran T., Wattanasirichaigoon, Duangrurdee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151034/ https://www.ncbi.nlm.nih.gov/pubmed/31936501 http://dx.doi.org/10.3390/diseases8010002 |
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