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Synthesis and Characterization of Polyfumarateurethane Nanoparticles for Sustained Release of Bupivacaine

Biodegradable polyfumarateurethane (PFU) for use as a bupivacaine delivery vehicle, synthesized using di-(2-hydroxypropyl fumarate) (DHPF), polyethylene glycol (PEG) and 1,6-hexamethylene diisocyanate (HMDI), was designed to be degradable through the hydrolysis and enzymatic degradation of the ester...

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Detalles Bibliográficos
Autores principales: Park, Soo-Yong, Kang, Jiin, Yoon, Ji-Young, Chung, Ildoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151093/
https://www.ncbi.nlm.nih.gov/pubmed/32245172
http://dx.doi.org/10.3390/pharmaceutics12030281