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Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery
Drug delivery is a fascinating research field with several development opportunities. Great attention is now focused on colloidal systems, nanoparticles, and nanogels and on the possibility of modifying them in order to obtain precise targeted drug delivery systems. The aim of this review is to give...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151136/ https://www.ncbi.nlm.nih.gov/pubmed/32033057 http://dx.doi.org/10.3390/gels6010006 |
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author | Pinelli, Filippo Perale, Giuseppe Rossi, Filippo |
author_facet | Pinelli, Filippo Perale, Giuseppe Rossi, Filippo |
author_sort | Pinelli, Filippo |
collection | PubMed |
description | Drug delivery is a fascinating research field with several development opportunities. Great attention is now focused on colloidal systems, nanoparticles, and nanogels and on the possibility of modifying them in order to obtain precise targeted drug delivery systems. The aim of this review is to give an overview of the main available surface functionalization and coating strategies that can be adopted in order to modify the selectivity of the nanoparticles in the delivery process and obtain a final system with great targeted drug delivery ability. We also highlight the most important fields of application of these kinds of delivery systems and we propose a comparison between the advantages and disadvantages of the described functionalization strategies. |
format | Online Article Text |
id | pubmed-7151136 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71511362020-04-20 Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery Pinelli, Filippo Perale, Giuseppe Rossi, Filippo Gels Review Drug delivery is a fascinating research field with several development opportunities. Great attention is now focused on colloidal systems, nanoparticles, and nanogels and on the possibility of modifying them in order to obtain precise targeted drug delivery systems. The aim of this review is to give an overview of the main available surface functionalization and coating strategies that can be adopted in order to modify the selectivity of the nanoparticles in the delivery process and obtain a final system with great targeted drug delivery ability. We also highlight the most important fields of application of these kinds of delivery systems and we propose a comparison between the advantages and disadvantages of the described functionalization strategies. MDPI 2020-02-04 /pmc/articles/PMC7151136/ /pubmed/32033057 http://dx.doi.org/10.3390/gels6010006 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Pinelli, Filippo Perale, Giuseppe Rossi, Filippo Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery |
title | Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery |
title_full | Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery |
title_fullStr | Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery |
title_full_unstemmed | Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery |
title_short | Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery |
title_sort | coating and functionalization strategies for nanogels and nanoparticles for selective drug delivery |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151136/ https://www.ncbi.nlm.nih.gov/pubmed/32033057 http://dx.doi.org/10.3390/gels6010006 |
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