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Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery

Drug delivery is a fascinating research field with several development opportunities. Great attention is now focused on colloidal systems, nanoparticles, and nanogels and on the possibility of modifying them in order to obtain precise targeted drug delivery systems. The aim of this review is to give...

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Detalles Bibliográficos
Autores principales: Pinelli, Filippo, Perale, Giuseppe, Rossi, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151136/
https://www.ncbi.nlm.nih.gov/pubmed/32033057
http://dx.doi.org/10.3390/gels6010006
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author Pinelli, Filippo
Perale, Giuseppe
Rossi, Filippo
author_facet Pinelli, Filippo
Perale, Giuseppe
Rossi, Filippo
author_sort Pinelli, Filippo
collection PubMed
description Drug delivery is a fascinating research field with several development opportunities. Great attention is now focused on colloidal systems, nanoparticles, and nanogels and on the possibility of modifying them in order to obtain precise targeted drug delivery systems. The aim of this review is to give an overview of the main available surface functionalization and coating strategies that can be adopted in order to modify the selectivity of the nanoparticles in the delivery process and obtain a final system with great targeted drug delivery ability. We also highlight the most important fields of application of these kinds of delivery systems and we propose a comparison between the advantages and disadvantages of the described functionalization strategies.
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spelling pubmed-71511362020-04-20 Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery Pinelli, Filippo Perale, Giuseppe Rossi, Filippo Gels Review Drug delivery is a fascinating research field with several development opportunities. Great attention is now focused on colloidal systems, nanoparticles, and nanogels and on the possibility of modifying them in order to obtain precise targeted drug delivery systems. The aim of this review is to give an overview of the main available surface functionalization and coating strategies that can be adopted in order to modify the selectivity of the nanoparticles in the delivery process and obtain a final system with great targeted drug delivery ability. We also highlight the most important fields of application of these kinds of delivery systems and we propose a comparison between the advantages and disadvantages of the described functionalization strategies. MDPI 2020-02-04 /pmc/articles/PMC7151136/ /pubmed/32033057 http://dx.doi.org/10.3390/gels6010006 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Pinelli, Filippo
Perale, Giuseppe
Rossi, Filippo
Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery
title Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery
title_full Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery
title_fullStr Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery
title_full_unstemmed Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery
title_short Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery
title_sort coating and functionalization strategies for nanogels and nanoparticles for selective drug delivery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151136/
https://www.ncbi.nlm.nih.gov/pubmed/32033057
http://dx.doi.org/10.3390/gels6010006
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