Bu-M-P-ing Iron: How BMP Signaling Regulates Muscle Growth and Regeneration

The bone morphogenetic protein (BMP) pathway is best known for its role in promoting bone formation, however it has been shown to play important roles in both development and regeneration of many different tissues. Recent work has shown that the BMP proteins have a number of functions in skeletal mu...

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Detalles Bibliográficos
Autores principales: Borok, Matthew J, Mademtzoglou, Despoina, Relaix, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151139/
https://www.ncbi.nlm.nih.gov/pubmed/32053985
http://dx.doi.org/10.3390/jdb8010004
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author Borok, Matthew J
Mademtzoglou, Despoina
Relaix, Frederic
author_facet Borok, Matthew J
Mademtzoglou, Despoina
Relaix, Frederic
author_sort Borok, Matthew J
collection PubMed
description The bone morphogenetic protein (BMP) pathway is best known for its role in promoting bone formation, however it has been shown to play important roles in both development and regeneration of many different tissues. Recent work has shown that the BMP proteins have a number of functions in skeletal muscle, from embryonic to postnatal development. Furthermore, complementary studies have recently demonstrated that specific components of the pathway are required for efficient muscle regeneration.
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spelling pubmed-71511392020-04-20 Bu-M-P-ing Iron: How BMP Signaling Regulates Muscle Growth and Regeneration Borok, Matthew J Mademtzoglou, Despoina Relaix, Frederic J Dev Biol Review The bone morphogenetic protein (BMP) pathway is best known for its role in promoting bone formation, however it has been shown to play important roles in both development and regeneration of many different tissues. Recent work has shown that the BMP proteins have a number of functions in skeletal muscle, from embryonic to postnatal development. Furthermore, complementary studies have recently demonstrated that specific components of the pathway are required for efficient muscle regeneration. MDPI 2020-02-11 /pmc/articles/PMC7151139/ /pubmed/32053985 http://dx.doi.org/10.3390/jdb8010004 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Borok, Matthew J
Mademtzoglou, Despoina
Relaix, Frederic
Bu-M-P-ing Iron: How BMP Signaling Regulates Muscle Growth and Regeneration
title Bu-M-P-ing Iron: How BMP Signaling Regulates Muscle Growth and Regeneration
title_full Bu-M-P-ing Iron: How BMP Signaling Regulates Muscle Growth and Regeneration
title_fullStr Bu-M-P-ing Iron: How BMP Signaling Regulates Muscle Growth and Regeneration
title_full_unstemmed Bu-M-P-ing Iron: How BMP Signaling Regulates Muscle Growth and Regeneration
title_short Bu-M-P-ing Iron: How BMP Signaling Regulates Muscle Growth and Regeneration
title_sort bu-m-p-ing iron: how bmp signaling regulates muscle growth and regeneration
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151139/
https://www.ncbi.nlm.nih.gov/pubmed/32053985
http://dx.doi.org/10.3390/jdb8010004
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