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A Novel, Circulating Tumor Cell Enrichment Method Reduces ARv7 False Positivity in Patients with Castration-Resistant Prostate Cancer

Background: The AR-V7 splice variant is a cause of castration-resistant prostate cancer (CRPC). However, testing for the presence of AR-V7 by real-time polymerase chain reaction (RT-PCR) shows AR-V7 positivity in healthy individuals. We hypothesized that the positivity reflects contamination by hema...

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Detalles Bibliográficos
Autores principales: Nakasato, Takehiko, Kusaka, Chiho, Ota, Mika, Hasebe, Yuki, Ueda, Kumiko, Unoki, Tsutomu, Oshinomi, Kazuhiko, Morita, Jun, Maeda, Yoshiko, Shichijo, Takeshi, Naoe, Michio, Ogawa, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151149/
https://www.ncbi.nlm.nih.gov/pubmed/32168745
http://dx.doi.org/10.3390/diagnostics10030151

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