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Enhanced Chondrogenic Differentiation Activities in Human Bone Marrow Aspirates via sox9 Overexpression Mediated by pNaSS-Grafted PCL Film-Guided rAAV Gene Transfer

Background: The delivery of therapeutic genes in sites of articular cartilage lesions using non-invasive, scaffold-guided gene therapy procedures is a promising approach to stimulate cartilage repair while protecting the cargos from detrimental immune responses, particularly when targeting chondrore...

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Detalles Bibliográficos
Autores principales: Venkatesan, Jagadeesh K., Meng, Weikun, Rey-Rico, Ana, Schmitt, Gertrud, Speicher-Mentges, Susanne, Falentin-Daudré, Céline, Leroux, Amélie, Madry, Henning, Migonney, Véronique, Cucchiarini, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151167/
https://www.ncbi.nlm.nih.gov/pubmed/32245159
http://dx.doi.org/10.3390/pharmaceutics12030280