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Epidemiological and clinical features of 125 Hospitalized Patients with COVID-19 in Fuyang, Anhui, China

OBJECTIVE: To investigate the epidemiological and clinical features of patients with COVID-19 in Anhui province of China. METHOD: In this descriptive study, we obtained epidemiological, demographic, manifestations, laboratory data and radiological findings of patients confirmed by real-time RT-PCR i...

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Autores principales: Wang, Ruirui, Pan, Min, Zhang, Xiumei, Han, Mingfeng, Fan, Xiaoyun, Zhao, Fengde, Miao, Manli, Xu, Jing, Guan, Minglong, Deng, Xia, Chen, Xu, Shen, Leilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151431/
https://www.ncbi.nlm.nih.gov/pubmed/32289565
http://dx.doi.org/10.1016/j.ijid.2020.03.070
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author Wang, Ruirui
Pan, Min
Zhang, Xiumei
Han, Mingfeng
Fan, Xiaoyun
Zhao, Fengde
Miao, Manli
Xu, Jing
Guan, Minglong
Deng, Xia
Chen, Xu
Shen, Leilei
author_facet Wang, Ruirui
Pan, Min
Zhang, Xiumei
Han, Mingfeng
Fan, Xiaoyun
Zhao, Fengde
Miao, Manli
Xu, Jing
Guan, Minglong
Deng, Xia
Chen, Xu
Shen, Leilei
author_sort Wang, Ruirui
collection PubMed
description OBJECTIVE: To investigate the epidemiological and clinical features of patients with COVID-19 in Anhui province of China. METHOD: In this descriptive study, we obtained epidemiological, demographic, manifestations, laboratory data and radiological findings of patients confirmed by real-time RT-PCR in the NO.2 People’s Hospital of Fuyang City from Jan 20 to Feb 9, 2020. Clinical outcomes were followed up to Feb 18, 2020. RESULTS: Of 125 patients infected SARS-CoV-2, the mean age was 38.76 years (SD, 13.799) and 71(56.8%) were male. Common symptoms include fever [116 (92.8%)], cough [102(81.6%)], and shortness of breath [57(45.6%)]. Lymphocytopenia developed in 48(38.4%) patients. 100(80.0%) patients showed bilateral pneumonia, 26(20.8%) patients showed multiple mottling and ground-glass opacity. All patients were given antiviral therapy. 19(15.2%) patients were transferred to the intensive care unit. By February 18, 47(37.6%) patients were discharged and none of patients died. Among the discharged patients, the median time of length of stay was 14.8 days (SD 4.16). CONCLUSION: In this single-center, retrospective, descriptive study, fever is the most common symptom. Old age, chronic underlying diseases and smoking history may be risk factors to worse condition. Certain laboratory inspection may contribute to the judgment of the severity of illness.
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spelling pubmed-71514312020-04-13 Epidemiological and clinical features of 125 Hospitalized Patients with COVID-19 in Fuyang, Anhui, China Wang, Ruirui Pan, Min Zhang, Xiumei Han, Mingfeng Fan, Xiaoyun Zhao, Fengde Miao, Manli Xu, Jing Guan, Minglong Deng, Xia Chen, Xu Shen, Leilei Int J Infect Dis Article OBJECTIVE: To investigate the epidemiological and clinical features of patients with COVID-19 in Anhui province of China. METHOD: In this descriptive study, we obtained epidemiological, demographic, manifestations, laboratory data and radiological findings of patients confirmed by real-time RT-PCR in the NO.2 People’s Hospital of Fuyang City from Jan 20 to Feb 9, 2020. Clinical outcomes were followed up to Feb 18, 2020. RESULTS: Of 125 patients infected SARS-CoV-2, the mean age was 38.76 years (SD, 13.799) and 71(56.8%) were male. Common symptoms include fever [116 (92.8%)], cough [102(81.6%)], and shortness of breath [57(45.6%)]. Lymphocytopenia developed in 48(38.4%) patients. 100(80.0%) patients showed bilateral pneumonia, 26(20.8%) patients showed multiple mottling and ground-glass opacity. All patients were given antiviral therapy. 19(15.2%) patients were transferred to the intensive care unit. By February 18, 47(37.6%) patients were discharged and none of patients died. Among the discharged patients, the median time of length of stay was 14.8 days (SD 4.16). CONCLUSION: In this single-center, retrospective, descriptive study, fever is the most common symptom. Old age, chronic underlying diseases and smoking history may be risk factors to worse condition. Certain laboratory inspection may contribute to the judgment of the severity of illness. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020-06 2020-04-11 /pmc/articles/PMC7151431/ /pubmed/32289565 http://dx.doi.org/10.1016/j.ijid.2020.03.070 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Wang, Ruirui
Pan, Min
Zhang, Xiumei
Han, Mingfeng
Fan, Xiaoyun
Zhao, Fengde
Miao, Manli
Xu, Jing
Guan, Minglong
Deng, Xia
Chen, Xu
Shen, Leilei
Epidemiological and clinical features of 125 Hospitalized Patients with COVID-19 in Fuyang, Anhui, China
title Epidemiological and clinical features of 125 Hospitalized Patients with COVID-19 in Fuyang, Anhui, China
title_full Epidemiological and clinical features of 125 Hospitalized Patients with COVID-19 in Fuyang, Anhui, China
title_fullStr Epidemiological and clinical features of 125 Hospitalized Patients with COVID-19 in Fuyang, Anhui, China
title_full_unstemmed Epidemiological and clinical features of 125 Hospitalized Patients with COVID-19 in Fuyang, Anhui, China
title_short Epidemiological and clinical features of 125 Hospitalized Patients with COVID-19 in Fuyang, Anhui, China
title_sort epidemiological and clinical features of 125 hospitalized patients with covid-19 in fuyang, anhui, china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151431/
https://www.ncbi.nlm.nih.gov/pubmed/32289565
http://dx.doi.org/10.1016/j.ijid.2020.03.070
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