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Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in Patients with Retinal Artery Occlusion
PURPOSE: This study aimed to compare the neutrophil-to-lymphocyte (NLR) and platelet-to-lymphocyte (PLR) ratios in patients with retinal artery occlusion (RAO) with those from a healthy control population and to identify the relationship between them. METHODS: Forty-six patients with RAO and fifty-o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PUBLISHED BY KNOWLEDGE E
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151506/ https://www.ncbi.nlm.nih.gov/pubmed/32308954 http://dx.doi.org/10.18502/jovr.v15i2.6737 |
Sumario: | PURPOSE: This study aimed to compare the neutrophil-to-lymphocyte (NLR) and platelet-to-lymphocyte (PLR) ratios in patients with retinal artery occlusion (RAO) with those from a healthy control population and to identify the relationship between them. METHODS: Forty-six patients with RAO and fifty-one healthy control subjects were included in this retrospective case-control study. RAO was diagnosed following an ophthalmic examination and fluorescein angiography (FA). Blood neutrophil, lymphocyte, and platelet counts were recorded for each of the 97 subjects, from which NLR and PLR values were calculated. RESULTS: There were 46 patients (28 male [M], 18 female [F]) in the RAO group and 51 patients (27 M, 24 F) in the control group. No significant differences were found between patients with RAO and the control subjects in terms of gender and age (P [Formula: see text] 0.05). Patients with RAO had significantly increased NLR values (2.85 [Formula: see text] 1.70) than the control subjects (1.63 [Formula: see text] 0.59, P < 0.001). The mean PLR in patients with RAO was 123.69 [Formula: see text] 64.98, while that in control subjects was 103.08 [Formula: see text] 36.95; there was no significant difference between the two groups (P = 0.055). A logistic regression analysis revealed that NLRs were 3.8 times higher in patients with RAO than in control subjects (odds ratio = 3.880; 95% confidence interval = 1.94 to 7.74; P < 0.001). CONCLUSION: NLRs were significantly increased in patients with RAO compared to the control subjects. |
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