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Synthesis and Properties of Zinc-Modified Hydroxyapatite

Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone implants based on hydroxyapatite modified with zinc i...

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Autores principales: Lytkina, Daria, Gutsalova, Anastasiya, Fedorishin, Dmitriy, Korotchenko, Natalya, Akhmedzhanov, Rafik, Kozik, Vladimir, Kurzina, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151590/
https://www.ncbi.nlm.nih.gov/pubmed/32093305
http://dx.doi.org/10.3390/jfb11010010
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author Lytkina, Daria
Gutsalova, Anastasiya
Fedorishin, Dmitriy
Korotchenko, Natalya
Akhmedzhanov, Rafik
Kozik, Vladimir
Kurzina, Irina
author_facet Lytkina, Daria
Gutsalova, Anastasiya
Fedorishin, Dmitriy
Korotchenko, Natalya
Akhmedzhanov, Rafik
Kozik, Vladimir
Kurzina, Irina
author_sort Lytkina, Daria
collection PubMed
description Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone implants based on hydroxyapatite modified with zinc ions. Zinc-modified hydroxyapatite was composed and synthesized. Using the XRD method, the phase composition was established. Using SEM, EPMA, and low-temperature nitrogen adsorption (BET) methods, surface properties were investigated. Antibacterial activity and biocompatibility have been established. The studied materials have antimicrobial activity; the samples did not cause significant changes in either the internal organs or the general condition of laboratory animals during the entire experiment.
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spelling pubmed-71515902020-04-20 Synthesis and Properties of Zinc-Modified Hydroxyapatite Lytkina, Daria Gutsalova, Anastasiya Fedorishin, Dmitriy Korotchenko, Natalya Akhmedzhanov, Rafik Kozik, Vladimir Kurzina, Irina J Funct Biomater Article Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone implants based on hydroxyapatite modified with zinc ions. Zinc-modified hydroxyapatite was composed and synthesized. Using the XRD method, the phase composition was established. Using SEM, EPMA, and low-temperature nitrogen adsorption (BET) methods, surface properties were investigated. Antibacterial activity and biocompatibility have been established. The studied materials have antimicrobial activity; the samples did not cause significant changes in either the internal organs or the general condition of laboratory animals during the entire experiment. MDPI 2020-02-20 /pmc/articles/PMC7151590/ /pubmed/32093305 http://dx.doi.org/10.3390/jfb11010010 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lytkina, Daria
Gutsalova, Anastasiya
Fedorishin, Dmitriy
Korotchenko, Natalya
Akhmedzhanov, Rafik
Kozik, Vladimir
Kurzina, Irina
Synthesis and Properties of Zinc-Modified Hydroxyapatite
title Synthesis and Properties of Zinc-Modified Hydroxyapatite
title_full Synthesis and Properties of Zinc-Modified Hydroxyapatite
title_fullStr Synthesis and Properties of Zinc-Modified Hydroxyapatite
title_full_unstemmed Synthesis and Properties of Zinc-Modified Hydroxyapatite
title_short Synthesis and Properties of Zinc-Modified Hydroxyapatite
title_sort synthesis and properties of zinc-modified hydroxyapatite
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151590/
https://www.ncbi.nlm.nih.gov/pubmed/32093305
http://dx.doi.org/10.3390/jfb11010010
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