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Synthesis and Properties of Zinc-Modified Hydroxyapatite
Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone implants based on hydroxyapatite modified with zinc i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151590/ https://www.ncbi.nlm.nih.gov/pubmed/32093305 http://dx.doi.org/10.3390/jfb11010010 |
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author | Lytkina, Daria Gutsalova, Anastasiya Fedorishin, Dmitriy Korotchenko, Natalya Akhmedzhanov, Rafik Kozik, Vladimir Kurzina, Irina |
author_facet | Lytkina, Daria Gutsalova, Anastasiya Fedorishin, Dmitriy Korotchenko, Natalya Akhmedzhanov, Rafik Kozik, Vladimir Kurzina, Irina |
author_sort | Lytkina, Daria |
collection | PubMed |
description | Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone implants based on hydroxyapatite modified with zinc ions. Zinc-modified hydroxyapatite was composed and synthesized. Using the XRD method, the phase composition was established. Using SEM, EPMA, and low-temperature nitrogen adsorption (BET) methods, surface properties were investigated. Antibacterial activity and biocompatibility have been established. The studied materials have antimicrobial activity; the samples did not cause significant changes in either the internal organs or the general condition of laboratory animals during the entire experiment. |
format | Online Article Text |
id | pubmed-7151590 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71515902020-04-20 Synthesis and Properties of Zinc-Modified Hydroxyapatite Lytkina, Daria Gutsalova, Anastasiya Fedorishin, Dmitriy Korotchenko, Natalya Akhmedzhanov, Rafik Kozik, Vladimir Kurzina, Irina J Funct Biomater Article Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone implants based on hydroxyapatite modified with zinc ions. Zinc-modified hydroxyapatite was composed and synthesized. Using the XRD method, the phase composition was established. Using SEM, EPMA, and low-temperature nitrogen adsorption (BET) methods, surface properties were investigated. Antibacterial activity and biocompatibility have been established. The studied materials have antimicrobial activity; the samples did not cause significant changes in either the internal organs or the general condition of laboratory animals during the entire experiment. MDPI 2020-02-20 /pmc/articles/PMC7151590/ /pubmed/32093305 http://dx.doi.org/10.3390/jfb11010010 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lytkina, Daria Gutsalova, Anastasiya Fedorishin, Dmitriy Korotchenko, Natalya Akhmedzhanov, Rafik Kozik, Vladimir Kurzina, Irina Synthesis and Properties of Zinc-Modified Hydroxyapatite |
title | Synthesis and Properties of Zinc-Modified Hydroxyapatite |
title_full | Synthesis and Properties of Zinc-Modified Hydroxyapatite |
title_fullStr | Synthesis and Properties of Zinc-Modified Hydroxyapatite |
title_full_unstemmed | Synthesis and Properties of Zinc-Modified Hydroxyapatite |
title_short | Synthesis and Properties of Zinc-Modified Hydroxyapatite |
title_sort | synthesis and properties of zinc-modified hydroxyapatite |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151590/ https://www.ncbi.nlm.nih.gov/pubmed/32093305 http://dx.doi.org/10.3390/jfb11010010 |
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