Repositioning the Sm-Binding Site in Saccharomyces cerevisiae Telomerase RNA Reveals RNP Organizational Flexibility and Sm-Directed 3′-End Formation

Telomerase RNA contains a template for synthesizing telomeric DNA and has been proposed to act as a flexible scaffold for holoenzyme protein subunits in the RNP. In Saccharomyces cerevisiae, the telomerase RNA, TLC1, is bound by the Sm(7) protein complex, which is required for stabilization of the p...

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Detalles Bibliográficos
Autores principales: Hass, Evan P., Zappulla, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151599/
https://www.ncbi.nlm.nih.gov/pubmed/32121425
http://dx.doi.org/10.3390/ncrna6010009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151599/
https://www.ncbi.nlm.nih.gov/pubmed/32121425
http://dx.doi.org/10.3390/ncrna6010009

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