Cargando…
Repositioning the Sm-Binding Site in Saccharomyces cerevisiae Telomerase RNA Reveals RNP Organizational Flexibility and Sm-Directed 3′-End Formation
Telomerase RNA contains a template for synthesizing telomeric DNA and has been proposed to act as a flexible scaffold for holoenzyme protein subunits in the RNP. In Saccharomyces cerevisiae, the telomerase RNA, TLC1, is bound by the Sm(7) protein complex, which is required for stabilization of the p...
Autores principales: | Hass, Evan P., Zappulla, David C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151599/ https://www.ncbi.nlm.nih.gov/pubmed/32121425 http://dx.doi.org/10.3390/ncrna6010009 |
Ejemplares similares
-
The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae
por: Hass, Evan P, et al.
Publicado: (2015) -
Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation
por: Prusty, Archana Bairavasundaram, et al.
Publicado: (2017) -
A 4-Base-Pair Core-Enclosing Helix in Telomerase RNA Is Essential for Activity and for Binding to the Telomerase Reverse Transcriptase Catalytic Protein Subunit
por: Mefford, Melissa A., et al.
Publicado: (2020) -
Structure–function analysis and genetic interactions of the Yhc1, SmD3, SmB, and Snp1 subunits of yeast U1 snRNP and genetic interactions of SmD3 with U2 snRNP subunit Lea1
por: Schwer, Beate, et al.
Publicado: (2015) -
Telomerase RNA biogenesis involves sequential binding by Sm and Lsm complexes
por: Tang, Wen, et al.
Publicado: (2012)