Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation and the Identification of Novel Therapeutic Targets

This review aims to highlight the role of long non-coding RNAs in mediating human immunodeficiency virus (HIV-1) viral replication, latency, disease susceptibility and progression. In particular, we focus on identifying possible lncRNA targets and their purported mechanisms of action for future drug...

Descripción completa

Detalles Bibliográficos
Autores principales: Ray, Roslyn M., Morris, Kevin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151623/
https://www.ncbi.nlm.nih.gov/pubmed/32183241
http://dx.doi.org/10.3390/ncrna6010012
_version_ 1783521293564379136
author Ray, Roslyn M.
Morris, Kevin V.
author_facet Ray, Roslyn M.
Morris, Kevin V.
author_sort Ray, Roslyn M.
collection PubMed
description This review aims to highlight the role of long non-coding RNAs in mediating human immunodeficiency virus (HIV-1) viral replication, latency, disease susceptibility and progression. In particular, we focus on identifying possible lncRNA targets and their purported mechanisms of action for future drug design or gene therapeutics.
format Online
Article
Text
id pubmed-7151623
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-71516232020-04-20 Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation and the Identification of Novel Therapeutic Targets Ray, Roslyn M. Morris, Kevin V. Noncoding RNA Review This review aims to highlight the role of long non-coding RNAs in mediating human immunodeficiency virus (HIV-1) viral replication, latency, disease susceptibility and progression. In particular, we focus on identifying possible lncRNA targets and their purported mechanisms of action for future drug design or gene therapeutics. MDPI 2020-03-13 /pmc/articles/PMC7151623/ /pubmed/32183241 http://dx.doi.org/10.3390/ncrna6010012 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ray, Roslyn M.
Morris, Kevin V.
Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation and the Identification of Novel Therapeutic Targets
title Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation and the Identification of Novel Therapeutic Targets
title_full Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation and the Identification of Novel Therapeutic Targets
title_fullStr Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation and the Identification of Novel Therapeutic Targets
title_full_unstemmed Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation and the Identification of Novel Therapeutic Targets
title_short Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation and the Identification of Novel Therapeutic Targets
title_sort long non-coding rnas mechanisms of action in hiv-1 modulation and the identification of novel therapeutic targets
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151623/
https://www.ncbi.nlm.nih.gov/pubmed/32183241
http://dx.doi.org/10.3390/ncrna6010012
work_keys_str_mv AT rayroslynm longnoncodingrnasmechanismsofactioninhiv1modulationandtheidentificationofnoveltherapeutictargets
AT morriskevinv longnoncodingrnasmechanismsofactioninhiv1modulationandtheidentificationofnoveltherapeutictargets

Ejemplares similares