The Emerging Role of ncRNAs and RNA-Binding Proteins in Mitotic Apparatus Formation

Mounting experimental evidence shows that non-coding RNAs (ncRNAs) serve a wide variety of biological functions. Recent studies suggest that a part of ncRNAs are critically important for supporting the structure of subcellular architectures. Here, we summarize the current literature demonstrating th...

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Detalles Bibliográficos
Autores principales: Ito, Kei K., Watanabe, Koki, Kitagawa, Daiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151635/
https://www.ncbi.nlm.nih.gov/pubmed/32245090
http://dx.doi.org/10.3390/ncrna6010013
Descripción
Sumario:Mounting experimental evidence shows that non-coding RNAs (ncRNAs) serve a wide variety of biological functions. Recent studies suggest that a part of ncRNAs are critically important for supporting the structure of subcellular architectures. Here, we summarize the current literature demonstrating the role of ncRNAs and RNA-binding proteins in regulating the assembly of mitotic apparatus, especially focusing on centrosomes, kinetochores, and mitotic spindles.

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