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In vitro evolution of herpes simplex virus 1 (HSV-1) reveals selection for syncytia and other minor variants in cell culture

The large dsDNA virus herpes simplex virus 1 (HSV-1) is considered to be genetically stable, yet it can rapidly evolve in response to strong selective pressures such as antiviral treatment. Deep sequencing has revealed that clinical and laboratory isolates of this virus exist as populations that con...

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Detalles Bibliográficos
Autores principales:	Kuny, Chad V, Bowen, Christopher D, Renner, Daniel W, Johnston, Christine M, Szpara, Moriah L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151645/ https://www.ncbi.nlm.nih.gov/pubmed/32296542 http://dx.doi.org/10.1093/ve/veaa013

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