4-Amino-1,2,4-triazole-3-thione as a Promising Scaffold for the Inhibition of Serine and Metallo-β-Lactamases

The emergence of bacteria that co-express serine- and metallo- carbapenemases is a threat to the efficacy of the available β-lactam antibiotic armamentarium. The 4-amino-1,2,4-triazole-3-thione scaffold has been selected as the starting chemical moiety in the design of a small library of β-Lactamase...

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Detalles Bibliográficos
Autores principales: Linciano, Pasquale, Gianquinto, Eleonora, Montanari, Martina, Maso, Lorenzo, Bellio, Pierangelo, Cebrián-Sastre, Esmeralda, Celenza, Giuseppe, Blázquez, Jesús, Cendron, Laura, Spyrakis, Francesca, Tondi, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151704/
https://www.ncbi.nlm.nih.gov/pubmed/32213902
http://dx.doi.org/10.3390/ph13030052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151704/
https://www.ncbi.nlm.nih.gov/pubmed/32213902
http://dx.doi.org/10.3390/ph13030052

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