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Molecular Mimicry and Autoimmunity

The term Molecular mimicry describes the sequence similarity between foreign (microorganism's peptides) and self peptides (the host's antigen). This phenomenon has been recently discovered as a one of the major mechanism in which there is a break-down of self-tolerance of the immune system...

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Detalles Bibliográficos
Autores principales: Maoz-Segal, Ramit, Andrade, Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151819/
http://dx.doi.org/10.1016/B978-0-444-63269-2.00054-4
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author Maoz-Segal, Ramit
Andrade, Paulo
author_facet Maoz-Segal, Ramit
Andrade, Paulo
author_sort Maoz-Segal, Ramit
collection PubMed
description The term Molecular mimicry describes the sequence similarity between foreign (microorganism's peptides) and self peptides (the host's antigen). This phenomenon has been recently discovered as a one of the major mechanism in which there is a break-down of self-tolerance of the immune system following autoimmunity. After a short preface, the chapter contains examples of common infectious agents and their role in autoimmune diseases. Later on, it describes the autoimmune diseases in which there was found a relation to infectious agents via molecular mimicry mechanism. The data is summarized in two tables.
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spelling pubmed-71518192020-04-13 Molecular Mimicry and Autoimmunity Maoz-Segal, Ramit Andrade, Paulo Infection and Autoimmunity Article The term Molecular mimicry describes the sequence similarity between foreign (microorganism's peptides) and self peptides (the host's antigen). This phenomenon has been recently discovered as a one of the major mechanism in which there is a break-down of self-tolerance of the immune system following autoimmunity. After a short preface, the chapter contains examples of common infectious agents and their role in autoimmune diseases. Later on, it describes the autoimmune diseases in which there was found a relation to infectious agents via molecular mimicry mechanism. The data is summarized in two tables. 2015 2015-02-06 /pmc/articles/PMC7151819/ http://dx.doi.org/10.1016/B978-0-444-63269-2.00054-4 Text en Copyright © 2015 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Maoz-Segal, Ramit
Andrade, Paulo
Molecular Mimicry and Autoimmunity
title Molecular Mimicry and Autoimmunity
title_full Molecular Mimicry and Autoimmunity
title_fullStr Molecular Mimicry and Autoimmunity
title_full_unstemmed Molecular Mimicry and Autoimmunity
title_short Molecular Mimicry and Autoimmunity
title_sort molecular mimicry and autoimmunity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151819/
http://dx.doi.org/10.1016/B978-0-444-63269-2.00054-4
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