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Acute Exacerbations in Patients With Idiopathic Pulmonary Fibrosis

In spite of many studies, the real nature, etiology, pathobiology, and therapy of acute exacerbation (AEx) of idiopathic pulmonary fibrosis (IPF) are not clear. It seemed that AEx-IPF may be an acute acceleration of the underlying fibroproliferative process triggered by various extrinsic or unknown...

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Autor principal: Kim, Dong Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151865/
http://dx.doi.org/10.1016/B978-0-323-48024-6.00011-2
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author Kim, Dong Soon
author_facet Kim, Dong Soon
author_sort Kim, Dong Soon
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description In spite of many studies, the real nature, etiology, pathobiology, and therapy of acute exacerbation (AEx) of idiopathic pulmonary fibrosis (IPF) are not clear. It seemed that AEx-IPF may be an acute acceleration of the underlying fibroproliferative process triggered by various extrinsic or unknown insults in the patients with IPF, who have a predisposition to abnormal wound healing and exaggerated fibrosis. This chapter summarizes the previous studies on etiology/triggering factors, risk factors, prognosis, and therapeutic trials with the introduction of the new consensus definition and diagnostic criteria, which remove “idiopathic” from the 2007 consensus definition, to improve the feasibility of future researches.
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spelling pubmed-71518652020-04-13 Acute Exacerbations in Patients With Idiopathic Pulmonary Fibrosis Kim, Dong Soon Interstitial Lung Disease Article In spite of many studies, the real nature, etiology, pathobiology, and therapy of acute exacerbation (AEx) of idiopathic pulmonary fibrosis (IPF) are not clear. It seemed that AEx-IPF may be an acute acceleration of the underlying fibroproliferative process triggered by various extrinsic or unknown insults in the patients with IPF, who have a predisposition to abnormal wound healing and exaggerated fibrosis. This chapter summarizes the previous studies on etiology/triggering factors, risk factors, prognosis, and therapeutic trials with the introduction of the new consensus definition and diagnostic criteria, which remove “idiopathic” from the 2007 consensus definition, to improve the feasibility of future researches. 2018 2017-05-19 /pmc/articles/PMC7151865/ http://dx.doi.org/10.1016/B978-0-323-48024-6.00011-2 Text en Copyright © 2018 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kim, Dong Soon
Acute Exacerbations in Patients With Idiopathic Pulmonary Fibrosis
title Acute Exacerbations in Patients With Idiopathic Pulmonary Fibrosis
title_full Acute Exacerbations in Patients With Idiopathic Pulmonary Fibrosis
title_fullStr Acute Exacerbations in Patients With Idiopathic Pulmonary Fibrosis
title_full_unstemmed Acute Exacerbations in Patients With Idiopathic Pulmonary Fibrosis
title_short Acute Exacerbations in Patients With Idiopathic Pulmonary Fibrosis
title_sort acute exacerbations in patients with idiopathic pulmonary fibrosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151865/
http://dx.doi.org/10.1016/B978-0-323-48024-6.00011-2
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