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Calpain-2 activity promotes aberrant endoplasmic reticulum stress-related apoptosis in hepatocytes

BACKGROUND: Calpain-2 is a Ca(2+)-dependent cysteine protease, and high calpain-2 activity can enhance apoptosis mediated by multiple triggers. AIM: To investigate whether calpain-2 can modulate aberrant endoplasmic reticulum (ER) stress-related apoptosis in rat hepatocyte BRL-3A cells. METHODS: BRL...

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Detalles Bibliográficos
Autores principales:	Xie, Ru-Jia, Hu, Xiao-Xia, Zheng, Lu, Cai, Shuang, Chen, Yu-Si, Yang, Yi, Yang, Ting, Han, Bing, Yang, Qin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2020
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152521/ https://www.ncbi.nlm.nih.gov/pubmed/32308346 http://dx.doi.org/10.3748/wjg.v26.i13.1450

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