p66shc siRNA Nanoparticles Ameliorate Chondrocytic Mitochondrial Dysfunction in Osteoarthritis

BACKGROUND: Osteoarthritis (OA) is the most common type of joint disease associated with cartilage breakdown. However, the role played by mitochondrial dysfunction in OA remains inadequately understood. Therefore, we investigated the role played by p66shc during oxidative damage and mitochondrial dy...

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Detalles Bibliográficos
Autores principales: Shin, Hyo Jung, Park, Hyewon, Shin, Nara, Shin, Juhee, Gwon, Do Hyeong, Kwon, Hyeok Hee, Yin, Yuhua, Hwang, Jeong-Ah, Hong, Jinpyo, Heo, Jun Young, Kim, Cuk-Seong, Joo, Yongbum, Kim, Youngmo, Kim, Jinhyun, Beom, Jaewon, Kim, Dong Woon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152540/
https://www.ncbi.nlm.nih.gov/pubmed/32308389
http://dx.doi.org/10.2147/IJN.S234198

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