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Pulmonary tuberculosis in a cohort of forensic autopsies: a preliminary study from Saudi Arabia
AIMS: The purpose of this study was to identify any cases of previously undiagnosed pulmonary tuberculosis during autopsy. METHODS: This prospective study investigated a cohort of deceased individuals that underwent a full external and internal postmortem examination at the Forensic Medicine Centre,...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152664/ https://www.ncbi.nlm.nih.gov/pubmed/32046547 http://dx.doi.org/10.1177/0300060519896434 |
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author | Madadin, Mohammed Menezes, Ritesh G. Al Tamimi, Dalal M. Kharoshah, Magdy A. Al Hamad, Mohammad Al-Nasser, Mona Al Madani, Osama M. |
author_facet | Madadin, Mohammed Menezes, Ritesh G. Al Tamimi, Dalal M. Kharoshah, Magdy A. Al Hamad, Mohammad Al-Nasser, Mona Al Madani, Osama M. |
author_sort | Madadin, Mohammed |
collection | PubMed |
description | AIMS: The purpose of this study was to identify any cases of previously undiagnosed pulmonary tuberculosis during autopsy. METHODS: This prospective study investigated a cohort of deceased individuals that underwent a full external and internal postmortem examination at the Forensic Medicine Centre, Dammam, Saudi Arabia. Gross pathology, histopathology and molecular pathology were used to identify pulmonary tuberculosis in forensic autopsy samples from the lungs. RESULTS: A total of 82 cases autopsied were included in the study. The mean ± SD age of the study cohort was 35.5 ± 10.3 years (range, 20–80 years). Males (n = 70; 85.37%) outnumbered females. The deceased were from 15 different countries. The number of Saudis was 16 (19.51%). The maximum number of non-Saudis was from India with 26 cases (31.71%). There were no cases of undiagnosed pulmonary tuberculosis detected for the first time at autopsy. CONCLUSIONS: Although the prevalence of pulmonary tuberculosis in forensic autopsy cases in this preliminary study was nil, we recommend further studies to be conducted on a larger scale and in different autopsy centres throughout Saudi Arabia to get an insight into the burden of clinically undiagnosed tuberculosis in the entire country. |
format | Online Article Text |
id | pubmed-7152664 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-71526642020-04-20 Pulmonary tuberculosis in a cohort of forensic autopsies: a preliminary study from Saudi Arabia Madadin, Mohammed Menezes, Ritesh G. Al Tamimi, Dalal M. Kharoshah, Magdy A. Al Hamad, Mohammad Al-Nasser, Mona Al Madani, Osama M. J Int Med Res Pre-Clinical Research Report AIMS: The purpose of this study was to identify any cases of previously undiagnosed pulmonary tuberculosis during autopsy. METHODS: This prospective study investigated a cohort of deceased individuals that underwent a full external and internal postmortem examination at the Forensic Medicine Centre, Dammam, Saudi Arabia. Gross pathology, histopathology and molecular pathology were used to identify pulmonary tuberculosis in forensic autopsy samples from the lungs. RESULTS: A total of 82 cases autopsied were included in the study. The mean ± SD age of the study cohort was 35.5 ± 10.3 years (range, 20–80 years). Males (n = 70; 85.37%) outnumbered females. The deceased were from 15 different countries. The number of Saudis was 16 (19.51%). The maximum number of non-Saudis was from India with 26 cases (31.71%). There were no cases of undiagnosed pulmonary tuberculosis detected for the first time at autopsy. CONCLUSIONS: Although the prevalence of pulmonary tuberculosis in forensic autopsy cases in this preliminary study was nil, we recommend further studies to be conducted on a larger scale and in different autopsy centres throughout Saudi Arabia to get an insight into the burden of clinically undiagnosed tuberculosis in the entire country. SAGE Publications 2020-02-12 /pmc/articles/PMC7152664/ /pubmed/32046547 http://dx.doi.org/10.1177/0300060519896434 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Pre-Clinical Research Report Madadin, Mohammed Menezes, Ritesh G. Al Tamimi, Dalal M. Kharoshah, Magdy A. Al Hamad, Mohammad Al-Nasser, Mona Al Madani, Osama M. Pulmonary tuberculosis in a cohort of forensic autopsies: a preliminary study from Saudi Arabia |
title | Pulmonary tuberculosis in a cohort of forensic autopsies: a preliminary study from Saudi Arabia |
title_full | Pulmonary tuberculosis in a cohort of forensic autopsies: a preliminary study from Saudi Arabia |
title_fullStr | Pulmonary tuberculosis in a cohort of forensic autopsies: a preliminary study from Saudi Arabia |
title_full_unstemmed | Pulmonary tuberculosis in a cohort of forensic autopsies: a preliminary study from Saudi Arabia |
title_short | Pulmonary tuberculosis in a cohort of forensic autopsies: a preliminary study from Saudi Arabia |
title_sort | pulmonary tuberculosis in a cohort of forensic autopsies: a preliminary study from saudi arabia |
topic | Pre-Clinical Research Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152664/ https://www.ncbi.nlm.nih.gov/pubmed/32046547 http://dx.doi.org/10.1177/0300060519896434 |
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