Frataxin-deficient cardiomyocytes present an altered thiol-redox state which targets actin and pyruvate dehydrogenase

Friedreich ataxia (FA) is a cardioneurodegenerative disease caused by deficient frataxin expression. This mitochondrial protein has been related to iron homeostasis, energy metabolism, and oxidative stress. Previously, we set up a cardiac cellular model of FA based on neonatal rat cardiac myocytes (...

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Detalles Bibliográficos
Autores principales: Purroy, Rosa, Medina-Carbonero, Marta, Ros, Joaquim, Tamarit, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152683/
https://www.ncbi.nlm.nih.gov/pubmed/32279039
http://dx.doi.org/10.1016/j.redox.2020.101520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152683/
https://www.ncbi.nlm.nih.gov/pubmed/32279039
http://dx.doi.org/10.1016/j.redox.2020.101520

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