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The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus

Antiviral drugs for managing infections with human coronaviruses are not yet approved, posing a serious challenge to current global efforts aimed at containing the outbreak of severe acute respiratory syndrome–coronavirus 2 (CoV-2). Remdesivir (RDV) is an investigational compound with a broad spectr...

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Detalles Bibliográficos
Autores principales:	Gordon, Calvin J., Tchesnokov, Egor P., Feng, Joy Y., Porter, Danielle P., Götte, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Editors' Picks
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152756/ https://www.ncbi.nlm.nih.gov/pubmed/32094225 http://dx.doi.org/10.1074/jbc.AC120.013056

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