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Online Databases and Non-coding RNAs in Cardiovascular Diseases

Cardiovascular disease is characterized by its highest morbidity and mortality. One of the main pathological basis of this disease is the dysregulation of gene expression. Non-coding RNA (ncRNA) is a kind of functional RNA, which is transcript from DNA but not translated into proteins. More and more...

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Autores principales: Chen, Rui, Shi, Chao, Yao, Jianhua, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153034/
https://www.ncbi.nlm.nih.gov/pubmed/32285405
http://dx.doi.org/10.1007/978-981-15-1671-9_3
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author Chen, Rui
Shi, Chao
Yao, Jianhua
Chen, Wei
author_facet Chen, Rui
Shi, Chao
Yao, Jianhua
Chen, Wei
author_sort Chen, Rui
collection PubMed
description Cardiovascular disease is characterized by its highest morbidity and mortality. One of the main pathological basis of this disease is the dysregulation of gene expression. Non-coding RNA (ncRNA) is a kind of functional RNA, which is transcript from DNA but not translated into proteins. More and more studies have established the important roles of ncRNAs, including transcription, RNA maturation, translation, protein degradation, and their involvement in the pathogenesis of diseases such as cancer and cardiovascular diseases. This chapter will focus on the biological functions of ncRNAs and their advances in cardiovascular disease. With the development of sequencing and computer technology, more and more databases can be easily obtained on the internet. In another part of this chapter, we will summarize some commonly used non-coding RNA databases, which can be easily and quickly used for relevant research.
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spelling pubmed-71530342020-04-13 Online Databases and Non-coding RNAs in Cardiovascular Diseases Chen, Rui Shi, Chao Yao, Jianhua Chen, Wei Non-coding RNAs in Cardiovascular Diseases Article Cardiovascular disease is characterized by its highest morbidity and mortality. One of the main pathological basis of this disease is the dysregulation of gene expression. Non-coding RNA (ncRNA) is a kind of functional RNA, which is transcript from DNA but not translated into proteins. More and more studies have established the important roles of ncRNAs, including transcription, RNA maturation, translation, protein degradation, and their involvement in the pathogenesis of diseases such as cancer and cardiovascular diseases. This chapter will focus on the biological functions of ncRNAs and their advances in cardiovascular disease. With the development of sequencing and computer technology, more and more databases can be easily obtained on the internet. In another part of this chapter, we will summarize some commonly used non-coding RNA databases, which can be easily and quickly used for relevant research. 2019-12-26 /pmc/articles/PMC7153034/ /pubmed/32285405 http://dx.doi.org/10.1007/978-981-15-1671-9_3 Text en © Springer Nature Singapore Pte Ltd. 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Chen, Rui
Shi, Chao
Yao, Jianhua
Chen, Wei
Online Databases and Non-coding RNAs in Cardiovascular Diseases
title Online Databases and Non-coding RNAs in Cardiovascular Diseases
title_full Online Databases and Non-coding RNAs in Cardiovascular Diseases
title_fullStr Online Databases and Non-coding RNAs in Cardiovascular Diseases
title_full_unstemmed Online Databases and Non-coding RNAs in Cardiovascular Diseases
title_short Online Databases and Non-coding RNAs in Cardiovascular Diseases
title_sort online databases and non-coding rnas in cardiovascular diseases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153034/
https://www.ncbi.nlm.nih.gov/pubmed/32285405
http://dx.doi.org/10.1007/978-981-15-1671-9_3
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