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Online Databases and Non-coding RNAs in Cardiovascular Diseases
Cardiovascular disease is characterized by its highest morbidity and mortality. One of the main pathological basis of this disease is the dysregulation of gene expression. Non-coding RNA (ncRNA) is a kind of functional RNA, which is transcript from DNA but not translated into proteins. More and more...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153034/ https://www.ncbi.nlm.nih.gov/pubmed/32285405 http://dx.doi.org/10.1007/978-981-15-1671-9_3 |
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author | Chen, Rui Shi, Chao Yao, Jianhua Chen, Wei |
author_facet | Chen, Rui Shi, Chao Yao, Jianhua Chen, Wei |
author_sort | Chen, Rui |
collection | PubMed |
description | Cardiovascular disease is characterized by its highest morbidity and mortality. One of the main pathological basis of this disease is the dysregulation of gene expression. Non-coding RNA (ncRNA) is a kind of functional RNA, which is transcript from DNA but not translated into proteins. More and more studies have established the important roles of ncRNAs, including transcription, RNA maturation, translation, protein degradation, and their involvement in the pathogenesis of diseases such as cancer and cardiovascular diseases. This chapter will focus on the biological functions of ncRNAs and their advances in cardiovascular disease. With the development of sequencing and computer technology, more and more databases can be easily obtained on the internet. In another part of this chapter, we will summarize some commonly used non-coding RNA databases, which can be easily and quickly used for relevant research. |
format | Online Article Text |
id | pubmed-7153034 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
record_format | MEDLINE/PubMed |
spelling | pubmed-71530342020-04-13 Online Databases and Non-coding RNAs in Cardiovascular Diseases Chen, Rui Shi, Chao Yao, Jianhua Chen, Wei Non-coding RNAs in Cardiovascular Diseases Article Cardiovascular disease is characterized by its highest morbidity and mortality. One of the main pathological basis of this disease is the dysregulation of gene expression. Non-coding RNA (ncRNA) is a kind of functional RNA, which is transcript from DNA but not translated into proteins. More and more studies have established the important roles of ncRNAs, including transcription, RNA maturation, translation, protein degradation, and their involvement in the pathogenesis of diseases such as cancer and cardiovascular diseases. This chapter will focus on the biological functions of ncRNAs and their advances in cardiovascular disease. With the development of sequencing and computer technology, more and more databases can be easily obtained on the internet. In another part of this chapter, we will summarize some commonly used non-coding RNA databases, which can be easily and quickly used for relevant research. 2019-12-26 /pmc/articles/PMC7153034/ /pubmed/32285405 http://dx.doi.org/10.1007/978-981-15-1671-9_3 Text en © Springer Nature Singapore Pte Ltd. 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Chen, Rui Shi, Chao Yao, Jianhua Chen, Wei Online Databases and Non-coding RNAs in Cardiovascular Diseases |
title | Online Databases and Non-coding RNAs in Cardiovascular Diseases |
title_full | Online Databases and Non-coding RNAs in Cardiovascular Diseases |
title_fullStr | Online Databases and Non-coding RNAs in Cardiovascular Diseases |
title_full_unstemmed | Online Databases and Non-coding RNAs in Cardiovascular Diseases |
title_short | Online Databases and Non-coding RNAs in Cardiovascular Diseases |
title_sort | online databases and non-coding rnas in cardiovascular diseases |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153034/ https://www.ncbi.nlm.nih.gov/pubmed/32285405 http://dx.doi.org/10.1007/978-981-15-1671-9_3 |
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